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L02727 2-Chloro-2',6'-dimethylacetanilide, 99%

CAS Number
1131-01-7
Synonyms
2-Chloro-2',6'-acetoxylidide
N-Chloroacetyl-2,6-dimethylaniline

Stock No. Size Price ($) Quantity Availability
L02727-09 10g 44.90
L02727-18 50g 176.00
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2-Chloro-2',6'-dimethylacetanilide, 99%

MDL
MFCD00000926
EINECS
214-460-7

Chemical Properties

Formula
C10H12ClNO
Formula Weight
197.67
Melting point
143-148°
Storage & Sensitivity
Ambient temperatures.
Solubility
Soluble in Chloroform, Methanol. Insoluble in water.

Applications

2-Chloro-2',6'-dimethylacetanilide is used in the determination of the enantiomers of tocainide in blood plasma by gas-liquid chromatography with electron-capture detection. It is a nonsteroidal antinflammatory drug.

Notes

Keep the container tightly closed in a cool, dry and well ventilated place. Incompatible with oxidizing agents.

Literature References

A J Sedman; J Gal. Simultaneous determination of the enantiomers of tocainide in blood plasma using gas-liquid chromatography with electron-capture detection. Journal of Chromatography B: Biomedical Sciences and Applications. 1984, 306, 155-164.

Galvez-Llompart; Maria M. Giner; Rosa C. Recio; Maria Candeletti; Sanzio Garcia-Domenech; Ramon. Application of Molecular Topology to the Search of Novel NSAIDs: Experimental Validation of Activity. Letters in Drug Design & Discovery.2010, 7, (8), 438-445.

GHS Hazard and Precautionary Statements

Hazard Statements: H315-H319-H335

Causes skin irritation. Causes serious eye irritation. May cause respiratory irritation.

Precautionary Statements: P261-P264b-P271-P280-P302+P352-P304+P340-P305+P351+P338-P312-P332+P313-P337+P313-P362-P501c

Avoid breathing dust/fume/gas/mist/vapours/spray. Wash face, hands and any exposed skin thoroughly after handling Use only outdoors or in a well-ventilated area. Wear protective gloves/protective clothing/eye protection/face protection. IF ON SKIN: Wash with plenty of soap and water. IF INHALED: Remove to fresh air and keep at rest in a position comfortable for breathing. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. Call a POISON CENTER or doctor/physician if you feel unwell. If skin irritation occurs: Get medical advice/attention. If eye irritation persists: Take off contaminated clothing and wash before reuse. Dispose of contents/ container to an approved waste disposal plant

Other References

Beilstein
781309
Harmonized Tariff Code
2924.29
TSCA
Yes

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