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It is employed as intermediate for pharmaceutical and organic synthesis.
Ralph J. Fessenden; Ray A. Hartman. Metabolic fate of phenyltrimethylsilane and phenyldimethylsilane. J. Med. Chem., 1970,13(1), 52-54.
J. A. Bedford; J. R. Bolton; A. Carrington; and R. H. Prince. The electron spin resonance spectra of the phenyltrimethylsilane and -germane anions: π-bonding between silicon and germanium and the aromatic ring. Trans. Faraday Soc.., 1963,5953-58.
Reagent, in combination with iodine, for cleavage of esters and ethers, cf Iodotrimethylsilane, A12902. Reported to be superior to TMS iodide for the cleavage of aryl ethers: Synthesis, 417 (1977).
Hazard Statements: H226-H315-H319-H335
Flammable liquid and vapour. Causes skin irritation. Causes serious eye irritation. May cause respiratory irritation.
Precautionary Statements: P210-P233-P235-P240-P241-P242-P243-P261-P264b-P271-P280-P303+P361+P353-P304+P340-P305+P351+P338-P312-P332+P313-P337+P313-P363-P370+P378q-P501c
Keep away from heat/sparks/open flames/hot surfaces. - No smoking. Keep container tightly closed. Keep cool. Ground/bond container and receiving equipment. Use explosion-proof electrical/ventilating/lighting/ equipment. Use only non-sparking tools. Take precautionary measures against static discharge. Avoid breathing dust/fume/gas/mist/vapours/spray. Wash face, hands and any exposed skin thoroughly after handling Use only outdoors or in a well-ventilated area. Wear protective gloves/protective clothing/eye protection/face protection. IF ON SKIN (or hair): Remove/Take off immediately all contaminated clothing. Rinse skin with water/shower. IF INHALED: Remove to fresh air and keep at rest in a position comfortable for breathing. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. Call a POISON CENTER or doctor/physician if you feel unwell. If skin irritation occurs: Get medical advice/attention. If eye irritation persists: Wash contaminated clothing before reuse. In case of fire: Use CO2, dry chemical, or foam Dispose of contents/ container to an approved waste disposal plant