2-(Methylsulfonyl)ethanol may be used as reagent in the synthesis of phenols from aryl fluorides. It may be used in the preparation of 2-(methylsulfonyl)ethyl N,N-bis(2-chloroethyl)phosphorodiamidate. 2-Hydroxyethyl Methyl Sulfone, is the versatile building block used in the synthesis of more complex sulfur containing compounds. It can be used for the studies of inhibitor and substrate moieties to acetylcholinesterase.
Rogers JF and Green DF. Mild conversion of electron deficient aryl fluorides to phenols using 2-(methylsulfonyl) ethanol.Tetrahedron Lett.,2002,43(19), 3585-87.
Monish Jain, et al. Sulfonyl-containing aldophosphamide analogues as novel anticancer prodrugs targeted against cyclophosphamide-resistant tumor cell lines.Journal of Medicinal Chemistry.,2004,47(15), 3843-3852.