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6373-50-8 - 4-Cyclohexylaniline, 97% - L03184 - Alfa Aesar

L03184 4-Cyclohexylaniline, 97%

CAS Number
6373-50-8
Synonyms

Size Price ($) Quantity Availability
1g 55.10
5g 190.00
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4-Cyclohexylaniline, 97%

MDL
MFCD00001454
EINECS
228-918-9

Chemical Properties

Formula
C12H17N
Formula Weight
175.28
Melting point
52-56°
Boiling Point
166°/13mm
Solubility
Insoluble in water.

Applications

4-Cyclohexylaniline is used as a starting material for the preparation of 1-cyclohexyl-4-nitroso-benzene. It is used as a reactant in nucleophilic acylation to form N-(4-cyclohexylphenyl)acetamide by reacting with acetyl halides. It is also involved in the synthesis of N-(4-cyclohexylphenyl)-2-morpholino-acetamide by reaction with 2-morpholinoacetyl fluoride. Further, it reacts with 4-bromo-4-oxo-butanoic acid to get 4-[(4-cyclohexylphenyl)amino]-4-oxo-butanoic acid.

Notes

Incompatible with strong oxidizing agents.

Literature References

Mou, J.; Park, A.; Cai, Y.; Yuan, J.; Yuan, C. Structure-activity relationship study of E6 as a novel necroptosis inducer. Bioorg. Med. Chem. Lett. 2015, 25 (15), 3057-3061.

Wei, W.; Wen, J.; Yang, D.; Sun, X.; You, J.; Suo, Y.; Wang, H. Iron-catalyzed three-component tandem process: a novel and convenient synthetic route to quinoline-2,4-dicarboxylates from arylamines, glyoxylic esters, and alpha-ketoesters. Tetrahedron 2013, 69 (50), 10747-10751.

GHS Hazard and Precautionary Statements

Hazard Statements: H302-H312

Harmful if swallowed. Harmful in contact with skin.

Precautionary Statements: P280h

Wear protective gloves/clothing.

Other References

Beilstein
2965799
Harmonized Tariff Code
2921.49
TSCA
No

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