I agree Our site saves small pieces of text information (cookies) on your device in order to deliver better content and for statistical purposes. You can disable the usage of cookies by changing the settings of your browser. By browsing our website without changing the browser settings you grant us permission to store that information on your device.
1-Methylpiperidine is a reactant for sp3 C-H Bond activation with ruthenium(II) catalysts and C(3)-alkylation of cyclic amines, One-pot synthesis of Z-cinnamic acids. It is used in the synthesis of Unsymmetrical ureas, Antibacterial imidazolium, pyrrolidinium, and piperidinium salts, C1-C16 segment of goniodomin A via palladium-catalyzed organostannane thioester coupling.
Amina A. Fakhroo; Hassan S. Bazzi; Adel Mostafa; Lamis Shahada. Synthesis, spectroscopic and thermal structural investigations of the charge-transfer complexes formed in the reaction of 1-methylpiperidine with ?- and π-acceptors.Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy. Chem.2010, 75 134-141.
G. Smith and G. A. Swan. The chemical effects of γ-radiation on organic systems. Part IV. The action of radiation on diethylamine, trimethylamine, benzylamine, phenethylamine, 1-methylpiperidine, N-methyldiethylamine, and t-butylamine.J. Chem. Soc. Chem.1962, 168 886-904.
Use of this base in the mixed anhydride method of peptide coupling reduces cleavage of the mixed anhydride at the "wrong" site: J. Org. Chem., 48, 2939 (1983). See Appendix 6.
Hazard Statements: H225-H302-H331-H314-H318
Highly flammable liquid and vapour. Harmful if swallowed. Toxic if inhaled. Causes severe skin burns and eye damage. Causes serious eye damage.
Precautionary Statements: P210-P280-P305+P351+P338-P309-P310a
Keep away from heat/sparks/open flames/hot surfaces. - No smoking. Wear protective gloves/protective clothing/eye protection/face protection. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. IF exposed or if you feel unwell: