Cookies disclaimer

I agree Our site saves small pieces of text information (cookies) on your device in order to deliver better content and for statistical purposes. You can disable the usage of cookies by changing the settings of your browser. By browsing our website without changing the browser settings you grant us permission to store that information on your device.

626-67-5 - 1-Methylpiperidine, 99% - L03398 - Alfa Aesar

L03398 1-Methylpiperidine, 99%

CAS Number
626-67-5
Synonyms

Size Price ($) Quantity Availability
10g 22.87
100g 30.78
500g 111.60
Add to Cart Add to Quote Request View Item

1-Methylpiperidine, 99%

MDL
MFCD00006491
EINECS
210-959-9

Chemical Properties

Formula
C6H13N
Formula Weight
99.18
Melting point
-50°
Boiling Point
105-107°
Flash Point
3°(37°F)
Density
0.816
Refractive Index
1.4378
Solubility
Fully miscible in water.

Applications

1-Methylpiperidine is a reactant for sp3 C-H Bond activation with ruthenium(II) catalysts and C(3)-alkylation of cyclic amines, One-pot synthesis of Z-cinnamic acids. It is used in the synthesis of Unsymmetrical ureas, Antibacterial imidazolium, pyrrolidinium, and piperidinium salts, C1-C16 segment of goniodomin A via palladium-catalyzed organostannane thioester coupling.

Notes

Store in cool place. Keep container tightly closed in a dry and well-ventilated place. Incompatible with.acids, Acid chlorides, Acid anhydrides, Strong oxidizing agents, Carbon dioxide.

Literature References

Amina A. Fakhroo; Hassan S. Bazzi; Adel Mostafa; Lamis Shahada. Synthesis, spectroscopic and thermal structural investigations of the charge-transfer complexes formed in the reaction of 1-methylpiperidine with ?- and π-acceptors.Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy. Chem.2010, 75 134-141.

G. Smith and G. A. Swan. The chemical effects of γ-radiation on organic systems. Part IV. The action of radiation on diethylamine, trimethylamine, benzylamine, phenethylamine, 1-methylpiperidine, N-methyldiethylamine, and t-butylamine.J. Chem. Soc. Chem.1962, 168 886-904.

Use of this base in the mixed anhydride method of peptide coupling reduces cleavage of the mixed anhydride at the "wrong" site: J. Org. Chem., 48, 2939 (1983). See Appendix 6.

GHS Hazard and Precautionary Statements

Hazard Statements: H225-H331-H302-H314-H318

Highly flammable liquid and vapour. Toxic if inhaled. Harmful if swallowed. Causes severe skin burns and eye damage. Causes serious eye damage.

Precautionary Statements: P210-P280-P305+P351+P338-P309-P310

Keep away from heat/sparks/open flames/hot surfaces. - No smoking. Wear protective gloves/protective clothing/eye protection/face protection. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. IF exposed or if you feel unwell: Immediately call a POISON CENTER or doctor/physician.

Other References

Beilstein
1073
Hazard Class
3
Packing Group
II
Harmonized Tariff Code
2933.39
TSCA
Yes
RTECS
TN1225000

Recommended

Recently Viewed

Chemicals

Life Science

Metals & Materials

Catalysts

Analytical & Labware