Cookies disclaimer

I agree Our site saves small pieces of text information (cookies) on your device in order to deliver better content and for statistical purposes. You can disable the usage of cookies by changing the settings of your browser. By browsing our website without changing the browser settings you grant us permission to store that information on your device.

50-28-2 - beta-Estradiol, 99% (dry wt.), ca 3% water - (8R,9S,13S,14S,17S)-13-methyl-7,8,9,11,12,13,14,15,16,17-decahydro-6H-cyclopenta[a]phenanthrene-3,17-diol - L03801 - Alfa Aesar

L03801 beta-Estradiol, 99% (dry wt.), ca 3% water

CAS Number
50-28-2
Synonyms
(8R,9S,13S,14S,17S)-13-methyl-7,8,9,11,12,13,14,15,16,17-decahydro-6H-cyclopenta[a]phenanthrene-3,17-diol

Size Price ($) Quantity Availability
1g 32.04
5g 111.60
25g 388.80
Add to Cart Add to Quote Request View Item

beta-Estradiol, 99% (dry wt.), ca 3% water

MDL
MFCD00003693
EINECS
200-023-8

Chemical Properties

Formula
C18H24O2
Formula Weight
272.39
Melting point
175-178°
Solubility
Soluble in dimethyl sulfoxide, ethanol , water, phosphate buffer saline, dimethyl formamide, acetone, dioxane and alkali hydroxides. Slightly soluble in vegetable oils.

Applications

β-Estradiol is the major estrogen secreted by the premenopausal ovary. It acts as an estrogenic hormone receptor (ER) agonist and activator of PI 3-kinase. Further, it is used in the treatment of infertility in women, prostate cancer and breast cancer. It is also employed as an agent of stimulating female puberty induction, as in the treatment of delayed puberty caused by hypogonadism or Turner's syndrome. In addition to this, it is used as part of the hormone replacement therapy for transgender women.

Notes

Incompatible with strong oxidizing agents.

Literature References

Liu, X.; Liu, Y.; Cheng, M.; Zhang, X.; Xiao, H. A metabolomics study of the inhibitory effect of 17-beta-estradiol on osteoclast proliferation and differentiation. Mol. Biosyst. 2015, 11 (2), 635-646.

Pooley, A. E.; Luong, M.; Hussain, A.; Nathan, B. P. Neurite outgrowth promoting effect of 17-beta estradiol is mediated through estrogen receptor alpha in an olfactory epithelium culture. Brain Res. 2015, 1624, 19-27.

GHS Hazard and Precautionary Statements

Hazard Statements: H350-H360

May cause cancer. May damage fertility or the unborn child.

Precautionary Statements: P201-P281-P202-P308+P313-P405-P501a

Obtain special instructions before use. Use personal protective equipment as required. Do not handle until all safety precautions have been read and understood. IF exposed or concerned: Get medical advice/attention. Store locked up. Dispose of contents/container in accordance with local/regional/national/international regulations.

Other References

Merck
14,3703
Beilstein
1914275
Harmonized Tariff Code
2906.19
TSCA
No
RTECS
KG2975000

Recommended

Recently Viewed

Chemicals

Life Science

Metals & Materials

Catalysts

Analytical & Labware