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(R)-(-)-2-Aminobutane is a chiral amine plays an important role in pharmaceutical chemistry and in organic synthesis as chiral auxiliary, which is used to determine the enantiomeric excess (ee).
Shcherbakova, E. G.; Minami, T.; Brega, V.; James, T. D.; Carvalho, P. O.; Anzenbacher Jr, P. Determination of Enantiomeric Excess in Amine Derivatives with Molecular Self-Assemblies. Angew. Chem. Int. Ed. 2015, 54 (24), 7130-7133.
Pilissao, C.; Carvalho, P. O.; Nascimento, M. G. The influence of conventional heating and microwave irradiation on the resolution of (RS)-sec-butylamine catalyzed by free or immobilized lipases. J. Braz. Chem. Soc. 2012, 23 (9), 1688-1697.
Joubioux, F. L.; Achour, O.; Bridiau, N.; Graber, M.; Maugard, T. Kinetic study of 2-butanol O-acylation and sec-butylamine N-acylation catalyzed by Candida antarctica lipase B. J. Mol. Catal. B: Enzym. 2011, 70 (3-4), 108-113.
Hazard Statements: H225-H302-H332-H314-H318
Highly flammable liquid and vapour. Harmful if swallowed. Harmful if inhaled. Causes severe skin burns and eye damage. Causes serious eye damage.
Precautionary Statements: P210-P260u-P303+P361+P353-P305+P351+P338-P405-P501a
Keep away from heat/sparks/open flames/hot surfaces. - No smoking. IF ON SKIN (or hair): Remove/Take off immediately all contaminated clothing. Rinse skin with water/shower. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. Store locked up. Dispose of contents/container in accordance with local/regional/national/international regulations.