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3-Methylindole is often used as a component of commercial fragrances and perfumes.It helps fluorescent guanosine analogue, which in a dimethoxytrityl, phosphoramidite protected form, can be site-specifically inserted into oligonucleotides through a 3?5?phosphodiester linkage using an automated DNA synthesizer
E. Hardin Strickland; Joseph Horwitz; Carolyn Billups. Near-ultraviolet absorption bands of tryptopan. Studies using indole and 3-methylindole as models.Biochemistry.1970, 9 (25), 4914-4921.
J Thornton-Manning; M L Appleton; F J Gonzalez and G S Yost. Metabolism of 3-methylindole by vaccinia-expressed P450 enzymes: correlation of 3-methyleneindolenine formation and protein-binding.JPET.1996, 276 (1), 21-29.
Hazard Statements: H303-H315-H319-H335
May be harmful if swallowed. Causes skin irritation. Causes serious eye irritation. May cause respiratory irritation.
Precautionary Statements: P261-P280a-P305+P351+P338-P304+P340-P405-P501a
Avoid breathing dust/fume/gas/mist/vapours/spray. Wear protective gloves and eye/face protection. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. IF INHALED: Remove to fresh air and keep at rest in a position comfortable for breathing. Store locked up. Dispose of contents/container in accordance with local/regional/national/international regulations.