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59-52-9 - 2,3-Dimercaptopropanol, 97% - BAL - Dimercaprol - L03953 - Alfa Aesar

L03953 2,3-Dimercaptopropanol, 97%

CAS Number
59-52-9
Synonyms
BAL
Dimercaprol

Size Price ($) Quantity Availability
1g 47.79
5g 123.20
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2,3-Dimercaptopropanol, 97%

MDL
MFCD00004864
EINECS
200-433-7

Chemical Properties

Formula
C3H8OS2
Formula Weight
124.22
Boiling Point
120°/15mm
Flash Point
>110°(230°F)
Density
1.244
Refractive Index
1.5740
Sensitivity
Air Sensitive
Solubility
Miscible with water, ether, ethanol, vegetable oils and acetone. Slightly miscible with chloroform.

Applications

British Anti-Lewisite. A chelator that inhibits sugar nucleotide degradation.2,3-Dimercaptopropanol is used as a chelating agent involved in the treatment of arsenic, antimony, lead, gold and mercury poisoning. It is also used as an antidote to the warfare agent Lewisite. Further, it is used for the treatment of Wilson's disease. In addition to this, it is used as an adjunct in the treatment of the acute encephalopathy of lead toxicity.

Notes

Air sensitive. Store in a cool place. Incompatible with bases, oxidizing agents, reducing agents and alkali metals.

Literature References

Chio, C. M.; Cheng, K. W.; Bishop, A. C. Direct Chemical Activation of a Rationally Engineered Signaling Enzyme. ChemBioChem 2015, 16 (12), 1735-1739.

Andries, C.; Manea, M.; Drochioiu, G.; Gradinaru, R. New insights into coenzyme A interaction with mercury ions provided by mass spectrometric and circular dichroism spectroscopic approaches. Eur. J. Mass Spectrom. 2015, 21 (2), 97-102.

GHS Hazard and Precautionary Statements

Hazard Statements: H301-H315-H319-H317

Toxic if swallowed. Causes skin irritation. Causes serious eye irritation. May cause an allergic skin reaction.

Precautionary Statements: P261-P280-P301+P310-P305+P351+P338-P362-P363-P321-P332+P313-P405-P501a

Avoid breathing dust/fume/gas/mist/vapours/spray. Wear protective gloves/protective clothing/eye protection/face protection. IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. Take off contaminated clothing and wash before reuse. Wash contaminated clothing before reuse. Specific treatment (see label). If skin irritation occurs: Get medical advice/attention. Store locked up. Dispose of contents/container in accordance with local/regional/national/international regulations.

Other References

Merck
14,3209
Beilstein
1732058
Hazard Class
6.1
Packing Group
III
Harmonized Tariff Code
2930.90
TSCA
Yes
RTECS
UB2625000

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