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British Anti-Lewisite. A chelator that inhibits sugar nucleotide degradation.2,3-Dimercaptopropanol is used as a chelating agent involved in the treatment of arsenic, antimony, lead, gold and mercury poisoning. It is also used as an antidote to the warfare agent Lewisite. Further, it is used for the treatment of Wilson's disease. In addition to this, it is used as an adjunct in the treatment of the acute encephalopathy of lead toxicity.
Chio, C. M.; Cheng, K. W.; Bishop, A. C. Direct Chemical Activation of a Rationally Engineered Signaling Enzyme. ChemBioChem 2015, 16 (12), 1735-1739.
Andries, C.; Manea, M.; Drochioiu, G.; Gradinaru, R. New insights into coenzyme A interaction with mercury ions provided by mass spectrometric and circular dichroism spectroscopic approaches. Eur. J. Mass Spectrom. 2015, 21 (2), 97-102.
Hazard Statements: H301-H315-H319-H317
Toxic if swallowed. Causes skin irritation. Causes serious eye irritation. May cause an allergic skin reaction.
Precautionary Statements: P260-P201-P280g-P304+P340-P405-P501a
Do not breathe dust/fume/gas/mist/vapours/spray. Obtain special instructions before use. Wear protective gloves. IF INHALED: Remove to fresh air and keep at rest in a position comfortable for breathing. Store locked up. Dispose of contents/container in accordance with local/regional/national/international regulations.