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1,4-Butanesultone is an alkylating agent used in synthetic chemistry. It serves as a wood preservative. It is employed as an intermediate of the organic sulfonation agent. Further, it is used as a raw material for electroplating intermediate. In addition to this, it finds application in active pharmaceutical ingredients, photographic materials, lithium battery and surface active agents.
For a review of the chemistry of sultones, see: Tetrahedron, 43, 1027 (1987).
Li, G.; Zhao, C.; Li, X.; Qi, D.; Liu, C.; Bu, F.; Na, H. Novel side-chain-type sulfonated diphenyl-based poly(arylene ether sulfone)s with a hydrogen-bonded network as proton exchange membranes. Polym. Chem. 2015, 6 (32), 5911-5920.
Shen, Y.; Sun, J. K.; Yi, Y. X.; Wang, B.; Xu, F.; Sun, R. C. One-pot synthesis of levulinic acid from cellulose in ionic liquids. Bioresour. Technol. 2015, 192, 812-816.
Hazard Statements: H302-H315-H320-H335-H341-H351
Harmful if swallowed. Causes skin irritation. Causes eye irritation. May cause respiratory irritation. Suspected of causing genetic defects. Suspected of causing cancer.
Precautionary Statements: P201-P202-P261-P264b-P270-P271-P280-P301+P312-P302+P352-P304+P340-P305+P351+P338-P308+P313-P312-P330-P332+P313-P337+P313-P362-P501c
Obtain special instructions before use. Do not handle until all safety precautions have been read and understood. Avoid breathing dust/fume/gas/mist/vapours/spray. Wash face, hands and any exposed skin thoroughly after handling Do not eat, drink or smoke when using this product. Use only outdoors or in a well-ventilated area. Wear protective gloves/protective clothing/eye protection/face protection. IF SWALLOWED: Call a POISON CENTER or doctor/physician if you feel unwell. IF ON SKIN: Wash with plenty of soap and water. IF INHALED: Remove to fresh air and keep at rest in a position comfortable for breathing. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. IF exposed or concerned: Get medical advice/attention. Rinse mouth. If skin irritation occurs: If eye irritation persists: Take off contaminated clothing and wash before reuse. Dispose of contents/ container to an approved waste disposal plant