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3219-63-4 - 1-Trimethylsilylmethanol, 95% - (Hydroxymethyl)trimethylsilane - L04251 - Alfa Aesar

L04251 1-Trimethylsilylmethanol, 95%

CAS Number
3219-63-4
Synonyms
(Hydroxymethyl)trimethylsilane

Size Price ($) Quantity Availability
1g 35.00
5g 148.00
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1-Trimethylsilylmethanol, 95%

MDL
MFCD00004596
EINECS
221-746-5

Chemical Properties

Formula
(CH3)3SiCH2OH
Formula Weight
104.23
Boiling Point
121-122°
Flash Point
31°(87°F)
Density
0.827
Refractive Index
1.4190
Solubility
Fully miscible in water.

Applications

1-Trimethylsilylmethanol is used as nucleophile to resolve the racemate obtained from enantioselective esterification of naproxen (2-(6-methoxy-2-naphthyl) propionic acid) by lipases. It was also used as a nucleophilic hydroxymethylation agent.

Notes

Store at 4°C. Incompatible with oxidizing agents. Store in cool place. Keep container tightly closed in a dry and well-ventilated place.

GHS Hazard and Precautionary Statements

Hazard Statements: H226

Flammable liquid and vapour.

Precautionary Statements: P210-P280-P240-P241-P233-P242-P243-P303+P361+P353-P403+P235-P501a

Keep away from heat/sparks/open flames/hot surfaces. - No smoking. Wear protective gloves/protective clothing/eye protection/face protection. Ground/bond container and receiving equipment. Use explosion-proof electrical/ventilating/lighting/ equipment. Keep container tightly closed. Use only non-sparking tools. Take precautionary measures against static discharge. IF ON SKIN (or hair): Remove/Take off immediately all contaminated clothing. Rinse skin with water/shower. Store in a well-ventilated place. Keep cool. Dispose of contents/container in accordance with local/regional/national/international regulations.

Other References

Beilstein
1731486
Hazard Class
3
Packing Group
III
Harmonized Tariff Code
2931.90
TSCA
Yes
RTECS
PC4100000

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