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7144-08-3 - Cholesteryl chloroformate - Chloroformic acid cholesteryl ester - L04801 - Alfa Aesar

L04801 Cholesteryl chloroformate

CAS Number
7144-08-3
Synonyms
Chloroformic acid cholesteryl ester

Size Price ($) Quantity Availability
25g 38.70
100g 92.40
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Cholesteryl chloroformate

MDL
MFCD00003633
EINECS
230-447-9

Chemical Properties

Formula
C28H45ClO2
Formula Weight
449.12
Melting point
116-120°
Sensitivity
Moisture Sensitive
Solubility
Soluble in methylene chloride, chloroform, acetone, toluene and benzene. Slightly soluble in methanol and ethanol.

Applications

Cholesteryl chloroformate is used in the preparation of hydrophobized chitosan oligosaccharide, which finds application as an efficient gene carrier. It acts as an initiator in the polymerization of methyl methacrylate.

Notes

Moisture sensitive. Incompatible with strong bases and strong oxidizing agents.

Literature References

Has been used as a means of introducing a bulky, organic-soluble group for the isolation of small quantities of primary and secondary amines from aqueous solution: Can. J. Chem., 31, 688 (1953).

Chou, T. H.; Chen, C. W. Synthesis, Self-assembly, and in vitro Biocompatibility of a Novel Steroidal Oxime. Current Pharm. Biotechnol. 2015, 16 (12), 1104-1110.

Podder, D.; Sasmal, S.; Haldar, D. Sonication Responsive Gelator: Synthesis and Applications. Curr. Org. Synth. 2015, 12 (4), 440-456.

GHS Hazard and Precautionary Statements

Hazard Statements: H314-H318

Causes severe skin burns and eye damage. Causes serious eye damage.

Precautionary Statements: P280-P305+P351+P338-P309-P310a

Wear protective gloves/protective clothing/eye protection/face protection. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. IF exposed or if you feel unwell:

Other References

Beilstein
3223154
Hazard Class
8
Packing Group
II
Harmonized Tariff Code
2915.90
TSCA
Yes

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