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L04801 Cholesteryl chloroformate

CAS Number
7144-08-3
Synonyms
Chloroformic acid cholesteryl ester

Stock No. Size Price ($) Quantity Availability
L04801-14 25g 40.30
L04801-22 100g 99.00
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Cholesteryl chloroformate

MDL
MFCD00003633
EINECS
230-447-9

Chemical Properties

Formula
C28H45ClO2
Formula Weight
449.12
Melting point
116-120°
Storage & Sensitivity
Keep Cold. Moisture Sensitive.
Solubility
Soluble in methylene chloride, chloroform, acetone, toluene and benzene. Slightly soluble in methanol and ethanol.

Applications

Cholesteryl chloroformate is used in the preparation of hydrophobized chitosan oligosaccharide, which finds application as an efficient gene carrier. It acts as an initiator in the polymerization of methyl methacrylate.

Notes

Moisture sensitive. Incompatible with strong bases and strong oxidizing agents.

Literature References

Has been used as a means of introducing a bulky, organic-soluble group for the isolation of small quantities of primary and secondary amines from aqueous solution: Can. J. Chem., 31, 688 (1953).

Chou, T. H.; Chen, C. W. Synthesis, Self-assembly, and in vitro Biocompatibility of a Novel Steroidal Oxime. Current Pharm. Biotechnol. 2015, 16 (12), 1104-1110.

Podder, D.; Sasmal, S.; Haldar, D. Sonication Responsive Gelator: Synthesis and Applications. Curr. Org. Synth. 2015, 12 (4), 440-456.

GHS Hazard and Precautionary Statements

Hazard Statements: H314

Causes severe skin burns and eye damage.

Precautionary Statements: P260-P264b-P280-P301+P330+P331-P303+P361+P353-P304+P340-P305+P351+P338-P310-P363-P501c

Do not breathe dust/fume/gas/mist/vapours/spray. Wash face, hands and any exposed skin thoroughly after handling Wear protective gloves/protective clothing/eye protection/face protection. IF SWALLOWED: Rinse mouth. Do NOT induce vomiting. IF ON SKIN (or hair): Remove/Take off immediately all contaminated clothing. Rinse skin with water/shower. IF INHALED: Remove to fresh air and keep at rest in a position comfortable for breathing. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. Immediately call a POISON CENTER or doctor/physician. Wash contaminated clothing before reuse. Dispose of contents/ container to an approved waste disposal plant

Other References

Beilstein
3223154
Hazard Class
8
Packing Group
II
Harmonized Tariff Code
2915.90
TSCA
Yes

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