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1145-93-3 - Diethyl 4-methoxybenzylphosphonate, 98+% - 4-Methoxybenzylphosphonic acid diethyl ester - L05226 - Alfa Aesar

L05226 Diethyl 4-methoxybenzylphosphonate, 98+%

CAS Number
1145-93-3
Synonyms
4-Methoxybenzylphosphonic acid diethyl ester

Size Price ($) Quantity Availability
10g 64.70
50g 237.00
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Diethyl 4-methoxybenzylphosphonate, 98+%

MDL
MFCD00015662
EINECS
214-548-5

Chemical Properties

Formula
C12H19O4P
Formula Weight
258.25
Boiling Point
136-138°/0.7mm
Flash Point
>110°(230°F)
Density
1.500
Refractive Index
1.5045
Solubility
Not miscible in water.

Applications

Diethyl 4-methoxybenzylphosphonate is used in synthesis of C-aryl glycosides. It acts as a reactant for synthesis of γ -Monofluorinated goniothalamin analogs via ring-opening hydrofluorination, stilbenoid derivatives with neuroprotective activity, resveratrol-chroman hybrids with antioxidant activity, Oligostilbenoids using regioselective cyclodehydration and arylation.

Notes

Store in cool place. Keep container tightly closed in a dry and well-ventilated place. Incompatible materials are Strong oxidizing agents.

Literature References

Frédérique Hauss,;Jiawei Liu; Alessandro Michelucci; Djalil Coowar; Eleonora Morga; Paul Heuschling; Bang Luu. Dual bioactivity of resveratrol fatty alcohols: differentiation of neural stem cells and modulation of neuroinflammation.Bioorganic & Medicinal Chemistry Letters.2007,17 (15), 4218-4222.

Jie Yang; Guo-Yun Liu; Dong-Liang Lu; Fang Dai; Yi-Ping Qian; Xiao-Ling Jin; Bo Zhou. Hybrid-increased radical-scavenging activity of resveratrol derivatives by incorporating a chroman moiety of vitamin E.Chemistry: A European Journal. 2010,16 (43), 12808-12813.

Used in synthesis of C-aryl glycosides: J. Org. Chem., 57, 5670 (1992).

Other References

Beilstein
2125148
Harmonized Tariff Code
2931.90
TSCA
No

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