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L05405 Potassium thioacetate, 98%

CAS Number
Thioacetic acid potassium salt

Stock No. Size Price ($) Quantity Availability
L05405-14 25g 43.60
L05405-22 100g 134.00
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Potassium thioacetate, 98%


Chemical Properties

Formula Weight
Melting point
ca 240° dec.
Storage & Sensitivity
Hygroscopic. Air Sensitive. Store under Argon. Ambient temperatures.
Soluble in water, methanol and some polar solvents. Insoluble in alkanes, ethers and most nonpolar solvents.


Potassium thioacetate is used for palladium mediated coupling with aryl halides and triflates leading to S-arylthioacetates and derivatives. It is also used as a reagent in the conversion of halides to thiols.


Air sensitive. Hygroscopic. Keep the container tightly closed in a dry and well-ventilated place. Incompatible with strong acids.

Literature References

Reagent for the conversion of halides and sulfonates to thiols via the thiol acetates, thus avoiding the problem of sulfide formation: J. Chem. Soc., 579 (1950).

Ortega, P.; Gómez, R.; de la Mata, F. J. Thiol ended carbosilane dendrimers. A multivalent platform for the binding of molecules of biological interest. Tetrahedron Lett. 2015, 56 (38), 5299-5302.

Zhao, J.; Wang, C.; Zhao, P.; Wen, X.; Lin, C. Bioreducible dextran-polyethylenimine conjugates regulate transgene expression distribution in vivo. J. Mater. Chem. B 2015, 3 (8), 1529-1536.

GHS Hazard and Precautionary Statements

Hazard Statements: H315-H319-H335

Causes skin irritation. Causes serious eye irritation. May cause respiratory irritation.

Precautionary Statements: P261-P264b-P271-P280-P302+P352-P304+P340-P305+P351+P338-P312-P332+P313-P337+P313-P362-P501c

Avoid breathing dust/fume/gas/mist/vapours/spray. Wash face, hands and any exposed skin thoroughly after handling Use only outdoors or in a well-ventilated area. Wear protective gloves/protective clothing/eye protection/face protection. IF ON SKIN: Wash with plenty of soap and water. IF INHALED: Remove to fresh air and keep at rest in a position comfortable for breathing. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. Call a POISON CENTER or doctor/physician if you feel unwell. If skin irritation occurs: Get medical advice/attention. If eye irritation persists: Take off contaminated clothing and wash before reuse. Dispose of contents/ container to an approved waste disposal plant

Other References

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