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Sodium methoxide is used as a base and a reagent in organic chemistry. It is useful in the synthesis of pharmaceuticals and agrochemicals. It acts as a nucleophile and is used in the production of methyl ethers. It serves as an initiator of anionic addition polymerization with ethylene oxide, forming a polyether with high molecular weight. It is involved in the production of biodiesel from vegetable oils and animal fats.
Zeng, D.; Li, R.; Feng, M.; Fang, T. Continuous Esterification of Free Fatty Acids in Crude Biodiesel by an Integrated Process of Supercritical Methanol and Sodium Methoxide Catalyst. Appl. Biochem. Biotechnol. 2014, 174 (4), 1484-1495.
Wuke, L.; Weijiang, Z.; Jiao, X.; Lei, Z. Study of the reaction between boron trifluoride methanol complex and sodium methoxide. J. Coord. Chem. 2014, 67 (9), 1530-1540.
Hazard Statements: H228-H251-H303-H314-H318
Flammable solid. Self-heating: may catch fire. May be harmful if swallowed. Causes severe skin burns and eye damage. Causes serious eye damage.
Precautionary Statements: P210-P260u-P303+P361+P353-P305+P351+P338-P405-P501a
Keep away from heat/sparks/open flames/hot surfaces. - No smoking. Do not breathe dusts or mists. IF ON SKIN (or hair): Remove/Take off immediately all contaminated clothing. Rinse skin with water/shower. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. Store locked up. Dispose of contents/container in accordance with local/regional/national/international regulations.