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2-Amino-5-chlorothiazole hydrochloride is used as starting reagent in the synthesis of 2-chloro-6-methylimidazo[2,1-b]thiazole. It is used as reactant for preparation of biologically active thiazole derivatives.
Aldo Andreani; Massimiliano Granaiola; Alberto Leoni; Alessandra Locatelli; Rita Morigi; Mirella Rambaldi; Maurizio Recanatini; Giorgio Lenaz; Romana Fato; Christian Bergamini. Effects of new ubiquinone-imidazo[2,1-b]thiazoles on mitochondrial complex I (NADH-ubiquinone reductase) and on mitochondrial permeability transition pore. Bioorganic & Medicinal Chemistry. 2004, 12, (21), 5525-5532.
K Tsuji; T Ogino; N Seki; M Sawada; Y Sudo; F Nishigaki; T Manda; M Matsuo. Synthesis and effects of novel thiazole derivatives against thrombocytopenia. Bioorganic & Medicinal Chemistry Letters. 1998, 8, (18), 2473-2478.
Hazard Statements: H301
Toxic if swallowed.
Precautionary Statements: P264-P270-P301+P310a-P321-P405-P501a
Wash thoroughly after handling. Do not eat, drink or smoke when using this product. IF SWALLOWED: Immediately call a POISON CENTER/doctor Specific treatment (see label). Store locked up. Dispose of contents/container in accordance with local/regional/national/international regulations.