Cookies disclaimer

I agree Our site saves small pieces of text information (cookies) on your device in order to deliver better content and for statistical purposes. You can disable the usage of cookies by changing the settings of your browser. By browsing our website without changing the browser settings you grant us permission to store that information on your device.

L05913 6,9-Dichloro-2-methoxyacridine, 98%

CAS Number
86-38-4
Synonyms
3,9-Dichloro-7-methoxyacridine

Stock No. Size Price ($) Quantity Availability
L05913-06 5g 31.00
L05913-14 25g 96.70
Add to Cart Bulk/Specialty Print Quote View Item

6,9-Dichloro-2-methoxyacridine, 98%

MDL
MFCD00005028
EINECS
201-666-7

Chemical Properties

Formula
C14H9Cl2NO
Formula Weight
278.14
Melting point
163-165°
Storage & Sensitivity
Ambient temperatures.
Solubility
Insoluble in water.

Applications

6,9-Dichloro-2-methoxyacridine is used to prepare 6-chloro-2-methoxy-acridin-9-ylamine by reacting with phenol and ammonium carbonate. It is used in the preparation of 9-amino-6-chloro-2-methoxyacridine, N'-(6-Chloro-2-methoxy-acridin-9-yl)-heptylamine and N,N'-bis-(6-chloro-2-methoxy-acridin-9-yl)-hexane-1,6-diamine. Further, it is involved in the preparation of 4-aminoquinoline and 9-aminoacridine derivatives by reaction with quinolizidinylalkylamines.

Notes

Incompatible with oxidizing agents.

Literature References

Staderini, M.; Bolognesi, M. L.; Menéndez, J. C. Lewis Acid-Catalyzed Generation of C-C and C-N Bonds on pi-Deficient Heterocyclic Substrates. Adv. Synth. Catal. 2015, 357 (1), 185-195.

Wang, T.; Goodall, M. L.; Gonzales, P.; Sepulveda, M.; Martin, K. R.; Gately, S.; MacKeigan, J. P. Synthesis of Improved Lysomotropic Autophagy Inhibitors. J. Med. Chem. 2015, 58 (7), 3025-3035.

GHS Hazard and Precautionary Statements

Hazard Statements: H315-H317-H319-H334-H335

Causes skin irritation. May cause an allergic skin reaction. Causes serious eye irritation. May cause allergy or asthma symptoms or breathing difficulties if inhaled. May cause respiratory irritation.

Precautionary Statements: P264b-P271-P272-P280-P285-P302+P352-P304+P340-P305+P351+P338-P333+P313-P342+P311-P362-P501c

Wash face, hands and any exposed skin thoroughly after handling Use only outdoors or in a well-ventilated area. Contaminated work clothing should not be allowed out of the workplace. Wear protective gloves/protective clothing/eye protection/face protection. In case of inadequate ventilation wear respiratory protection. IF ON SKIN: Wash with plenty of soap and water. IF INHALED: Remove to fresh air and keep at rest in a position comfortable for breathing. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. If skin irritation or rash occurs: Get medical advice/attention. If experiencing respiratory symptoms: Call a POISON CENTER or doctor/physician. Take off contaminated clothing and wash before reuse. Dispose of contents/ container to an approved waste disposal plant

Other References

Beilstein
226309
Harmonized Tariff Code
2933.99
TSCA
No

Recommended

Recently Viewed

Chemicals

Life Science

Metals & Materials

Catalysts

Analytical & Labware