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2-Chlorophenyl cyclopentyl ketone is used as a reagent in the preparation of bicyclic and polycyclic aromatic hydrocarbons. It acts as a pharmaceutical intermediate and also as an intermediate of ketamine.
Li, Y.; Coller, J. K.; Hutchinson, M. R.; Klein, K.; Zanger, U. M.; Stanley, N. J.; Abell, A. D.; Somogyi, A. A. The CYP2B6* 6 allele significantly alters the N-demethylation of ketamine enantiomers in vitro. Drug Metab. Dispos. 2013, 41 (6), 1264-1272.
Jose, J.; Gamage, S. A.; Harvey, M. G.; Voss, L. J.; Sleigh, J. W.; Denny, W. A. Structure-activity relationships for ketamine esters as short-acting anaesthetics. Bioorg. Med. Chem. 2013, 21 (17), 5098-5106.