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6740-85-8 - 2-Chlorophenyl cyclopentyl ketone, 97% - (2-Chlorobenzoyl)cyclopentane - L06448 - Alfa Aesar

L06448 2-Chlorophenyl cyclopentyl ketone, 97%

CAS Number
6740-85-8
Synonyms
(2-Chlorobenzoyl)cyclopentane

Size Price ($) Quantity Availability
10g 49.30
50g 182.00
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2-Chlorophenyl cyclopentyl ketone, 97%

MDL
MFCD00038367
EINECS
229-802-0

Chemical Properties

Formula
C12H13ClO
Formula Weight
208.69
Boiling Point
130°/5mm
Flash Point
>100°(212°F)
Density
1.16
Refractive Index
1.5470
Solubility
Slightly miscible with chloroform and ethyl acetate.

Applications

2-Chlorophenyl cyclopentyl ketone is used as a reagent in the preparation of bicyclic and polycyclic aromatic hydrocarbons. It acts as a pharmaceutical intermediate and also as an intermediate of ketamine.

Notes

Incompatible with oxidizing agents.

Literature References

Li, Y.; Coller, J. K.; Hutchinson, M. R.; Klein, K.; Zanger, U. M.; Stanley, N. J.; Abell, A. D.; Somogyi, A. A. The CYP2B6* 6 allele significantly alters the N-demethylation of ketamine enantiomers in vitro. Drug Metab. Dispos. 2013, 41 (6), 1264-1272.

Jose, J.; Gamage, S. A.; Harvey, M. G.; Voss, L. J.; Sleigh, J. W.; Denny, W. A. Structure-activity relationships for ketamine esters as short-acting anaesthetics. Bioorg. Med. Chem. 2013, 21 (17), 5098-5106.

Other References

Beilstein
1873022
Harmonized Tariff Code
2914.79
TSCA
No

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