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Cyclohexanemethylamine was used in the synthesis of Schiff?s base ligand, 4-methyl-2,6-bis(cyclohexylmethyliminomethyl)-phenol, which forms hexanuclear zinc(II) complexes. It was used during the synthesis of 1-acyl-4 cycloalkyl/arylsemicarbazides and 1-acyl-5-benzyloxy/hydroxyl carbamoylcarbazides from the nonsteroidal anti-inflammatory drugs.
Partha Roy; Mario Manassero; Koushik Dhara; Pradyot Banerjee. Synthesis, characterization and fluorescence properties of hexanuclear zinc(II) complexes. Polyhedron. 2009, 28,(6), 1133-1137.
I.Perkovic; I.Butula; M.Kralj; I.Martin-Kleiner; J.Balzarini; D.Hadjipavlou-Litina; A.M.Katsori; B.Zorc. Novel NSAID 1-acyl-4-cycloalkyl/arylsemicarbazides and 1-acyl-5-benzyloxy/hydroxy carbamoylcarbazides as potential anticancer agents and antioxidants. European Journal of Medicinal Chemistry. 2012, 51,227-238.
Hazard Statements: H226-H302-H312-H314-H332-H335
Flammable liquid and vapour. Harmful if swallowed. Harmful in contact with skin. Causes severe skin burns and eye damage. Harmful if inhaled. May cause respiratory irritation.
Precautionary Statements: P210-P233-P235-P240-P241-P242-P243-P260-P264b-P270-P271-P280-P303+P361+P353-P304+P340-P305+P351+P338-P310-P330-P331-P363-P370+P378q-P501c
Keep away from heat/sparks/open flames/hot surfaces. - No smoking. Keep container tightly closed. Keep cool. Ground/bond container and receiving equipment. Use explosion-proof electrical/ventilating/lighting/ equipment. Use only non-sparking tools. Take precautionary measures against static discharge. Do not breathe dust/fume/gas/mist/vapours/spray. Wash face, hands and any exposed skin thoroughly after handling Do not eat, drink or smoke when using this product. Use only outdoors or in a well-ventilated area. Wear protective gloves/protective clothing/eye protection/face protection. IF ON SKIN (or hair): Remove/Take off immediately all contaminated clothing. Rinse skin with water/shower. IF INHALED: Remove to fresh air and keep at rest in a position comfortable for breathing. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. Immediately call a POISON CENTER or doctor/physician. Rinse mouth. Do NOT induce vomiting. Wash contaminated clothing before reuse. In case of fire: Use CO2, dry chemical, or foam Dispose of contents/ container to an approved waste disposal plant