L06692 6-Aminonicotinamide, 99%
SDS
6-Aminonicotinamide, 99%
Chemical Properties
Applications
6-Aminonicotinamide induces apoptosis in tumor cells. It is clinically used in disseminated neoplastic disease. It also acts as 6-phosphogluconate dehydrogenase inhibitor. It aids in the treatment of psoriasis. It is used as cancer chemotherapeutic drug in animals.
Notes
Literature References
Elisabeth Köhler; Hans-Jürgen Barrach; Diether Neubert. Inhibition of NADP dependent oxidoreductases by the 6-aminonicotinamide analogue of NADP.FEBS Letters.1970,6 225-228.
H. Herken; K. Lange. Blocking of pentose phosphate pathway in the brain of rats by 6-aminonicotinamide.Naunyn-Schmiedeberg's Archives of Pharmacology.1969,263 496-499.
GHS Hazard and Precautionary Statements
Hazard Statements: H360
May damage fertility or the unborn child.
Precautionary Statements: P201-P280-P202-P308+P313-P405-P501a
Obtain special instructions before use. Wear protective gloves/protective clothing/eye protection/face protection. Do not handle until all safety precautions have been read and understood. IF exposed or concerned: Get medical advice/attention. Store locked up. Dispose of contents/container in accordance with local/regional/national/international regulations.
