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6-Aminonicotinamide induces apoptosis in tumor cells. It is clinically used in disseminated neoplastic disease. It also acts as 6-phosphogluconate dehydrogenase inhibitor. It aids in the treatment of psoriasis. It is used as cancer chemotherapeutic drug in animals.
Elisabeth Köhler; Hans-Jürgen Barrach; Diether Neubert. Inhibition of NADP dependent oxidoreductases by the 6-aminonicotinamide analogue of NADP.FEBS Letters.1970,6 225-228.
H. Herken; K. Lange. Blocking of pentose phosphate pathway in the brain of rats by 6-aminonicotinamide.Naunyn-Schmiedeberg's Archives of Pharmacology.1969,263 496-499.
Hazard Statements: H360
May damage fertility or the unborn child.
Precautionary Statements: P201-P202-P281-P308+P313-P501c
Obtain special instructions before use. Do not handle until all safety precautions have been read and understood. Use personal protective equipment as required. IF exposed or concerned: Get medical advice/attention. Dispose of contents/ container to an approved waste disposal plant