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614-96-0 - 5-Methylindole, 99% - L06893 - Alfa Aesar

L06893 5-Methylindole, 99%

CAS Number
614-96-0
Synonyms

Size Price ($) Quantity Availability
1g 47.52
5g 195.54
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5-Methylindole, 99%

MDL
MFCD00005680
EINECS
210-400-9

Chemical Properties

Formula
C9H9N
Formula Weight
131.18
Melting point
58-61°
Boiling Point
100°/3mm
Sensitivity
Light Sensitive
Solubility
Insoluble in water.

Applications

5-Methylindole is used as reactant for preparation of pharmaceutically active 2-oxo-1-pyrrolidine analogues, potential anticancer immunomodulators, IL2-inducible T-cell kinase (ITK) inhibitors and CRTh2 antagonists.

Notes

Light sensitive. Incompatible with oxidizing agents and heat.

Literature References

Ran Jiang; Hai-Yan Xu; Xiao-Ping Xu; Xue-Qiang Chu; Shun-Jun Ji. Direct alkylation of indoles and amines by tert-enamides: facile access to pharmaceutically active 2-oxo-1-pyrrolidine analogues. Organic & Biomolecular Chemistry. 2011, 9,(16), 5659-5669.

 

Eduard Dolusic; Pierre Larrieu; Laurence Moineaux; Vincent Stroobant; Luc Pilotte; Didier Colau; Lionel Pochet; Benoit Van den Eynde; Bernard Masereel; Johan Wouters; Raphael Frederick. Tryptophan 2,3-dioxygenase (TDO) inhibitors. 3-(2-(pyridyl)ethenyl)indoles as potential anticancer immunomodulators. Journal of medicinal and pharmaceutical chemistry. 2011, 54,(15), 5320-5334.

GHS Hazard and Precautionary Statements

Hazard Statements: H315-H319-H335

Causes skin irritation. Causes serious eye irritation. May cause respiratory irritation.

Precautionary Statements: P261-P280-P305+P351+P338-P304+P340-P362-P312-P321-P405-P403+P233-P501a

Avoid breathing dust/fume/gas/mist/vapours/spray. Wear protective gloves/protective clothing/eye protection/face protection. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. IF INHALED: Remove to fresh air and keep at rest in a position comfortable for breathing. Take off contaminated clothing and wash before reuse. Call a POISON CENTER or doctor/physician if you feel unwell. Specific treatment (see label). Store locked up. Store in a well-ventilated place. Keep container tightly closed. Dispose of contents/container in accordance with local/regional/national/international regulations.

Other References

Beilstein
2228
Harmonized Tariff Code
2933.99
TSCA
No

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