Cookies disclaimer

I agree Our site saves small pieces of text information (cookies) on your device in order to deliver better content and for statistical purposes. You can disable the usage of cookies by changing the settings of your browser. By browsing our website without changing the browser settings you grant us permission to store that information on your device.

59-66-5 - Acetazolamide, 99% - 5-Acetamido-1,3,4-thiadiazole-2-sulfonamide - L07562 - Alfa Aesar

L07562 Acetazolamide, 99%

CAS Number
59-66-5
Synonyms
5-Acetamido-1,3,4-thiadiazole-2-sulfonamide

Size Price ($) Quantity Availability
5g 23.40
25g 58.50
Add to Cart Add to Quote Request View Item

Acetazolamide, 99%

MDL
MFCD00003105
EINECS
200-440-5

Chemical Properties

Formula
C4H6N4O3S2
Formula Weight
222.25
Melting point
ca 255° dec.
Solubility
Soluble in NH4OH (50 mg/mL), DMSO, Methanol and slightly soluble in Ethanol.

Applications

Acetazolamide acts as a carbonic anhydrase inhibitor which increases cerebral blood flow. It inhibits water permeability of membranes by interacting with aquaporins. It is used for the medical treatment of glaucoma, epileptic seizure, idiopathic intracranial hypertension, altitude sickness, cystinuria.

Notes

Store in cool place. Keep container tightly closed in a dry and well-ventilated place. Store away from oxidizing agents. Incompatible materials are oxidizing agents, bases.

Literature References

Junwei Gao; Xiaohua Wang; Yongjie Chang; Jianzhao Zhang; Qianliu Song; Heming Yu; Xuejun Li. Acetazolamide inhibits osmotic water permeability by interaction with aquaporin-1.Analytical Biochemistry.2006, 350 (2), 165-170 .

S. Nigel Cox, FRCS; Elizabeth Hay, MD; Alan C. Bird, MD. Treatment of Chronic Macular Edema With Acetazolamide.Arch Ophthalmol.1988, 106 (9), 1190-1195.

GHS Hazard and Precautionary Statements

Hazard Statements: H360-H303

May damage fertility or the unborn child. May be harmful if swallowed.

Precautionary Statements: P201-P281-P202-P312-P308+P313-P405-P501a

Obtain special instructions before use. Use personal protective equipment as required. Do not handle until all safety precautions have been read and understood. Call a POISON CENTER or doctor/physician if you feel unwell. IF exposed or concerned: Get medical advice/attention. Store locked up. Dispose of contents/container in accordance with local/regional/national/international regulations.

Other References

Merck
14,53
Beilstein
212994
Harmonized Tariff Code
2934.99
TSCA
Yes
RTECS
AC8225000

Recommended

  • A10913

    Calcium fluoride, 99%
  • A10926

    Diethylenetriaminepentaacetic acid, 98+%
  • A12054

    Isethionic acid sodium salt, 98%
  • 11287

    Gadolinium(III) chloride hexahydrate, REacton®, 99.99% (REO)
  • 14248

    Iodine, crystalline, 99.5%

Recently Viewed

Chemicals

Life Science

Metals & Materials

Catalysts

Analytical & Labware