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Acetazolamide acts as a carbonic anhydrase inhibitor which increases cerebral blood flow. It inhibits water permeability of membranes by interacting with aquaporins. It is used for the medical treatment of glaucoma, epileptic seizure, idiopathic intracranial hypertension, altitude sickness, cystinuria.
Junwei Gao; Xiaohua Wang; Yongjie Chang; Jianzhao Zhang; Qianliu Song; Heming Yu; Xuejun Li. Acetazolamide inhibits osmotic water permeability by interaction with aquaporin-1.Analytical Biochemistry.2006, 350 (2), 165-170 .
S. Nigel Cox, FRCS; Elizabeth Hay, MD; Alan C. Bird, MD. Treatment of Chronic Macular Edema With Acetazolamide.Arch Ophthalmol.1988, 106 (9), 1190-1195.
Hazard Statements: H303-H360
May be harmful if swallowed. May damage fertility or the unborn child.
Precautionary Statements: P201-P280-P312a-P308+P313-P405-P501a
Obtain special instructions before use. Wear protective gloves/protective clothing/eye protection/face protection. IF exposed or concerned: Get medical advice/attention. Store locked up. Dispose of contents/container in accordance with local/regional/national/international regulations.