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1-(n-Butyl)imidazole is used in the synthesis of a heterocyclic mesomeric betaine and 1-(1-butyl-3-imidazolio)propane-3-sulfonate (BIm3S). It acts as an N-coordinated ligand. It is used in the chiral separation of amino acids and anionic pharmaceuticals by capillary electrophoresis. It is used for preparation of substituted phenyl-containing imidazolium ionic liquid.
Nina Gonsior; Fabian Mohr; Helmut Ritter. Synthesis of mesomeric betaine compounds with imidazolium-enolate structure.Beilstein Journal of Organic Chemistry.2012, 8 390-397.
G M Smith; G G Duncan. A study of intravascular platelet aggregation by continuous platelet counting.Thrombosis Research.1981, 23 (3), 275-288.
Preferred ligand in a Cu(I)-catalyzed procedure for cyanation of heteroaryl bromides with potassium hexacyanoferrate(II), as an alternative to conventional routes with highly toxic metal cyanides: Synlett, 555 (2007).
Hazard Statements: H315-H318-H330-H335
Causes skin irritation. Causes serious eye damage. Fatal if inhaled. May cause respiratory irritation.
Precautionary Statements: P260-P264b-P271-P280-P284-P302+P352-P304+P340-P305+P351+P338-P310-P312-P332+P313-P362-P501c
Do not breathe dust/fume/gas/mist/vapours/spray. Wash face, hands and any exposed skin thoroughly after handling Use only outdoors or in a well-ventilated area. Wear protective gloves/protective clothing/eye protection/face protection. Wear respiratory protection. IF ON SKIN: Wash with plenty of soap and water. IF INHALED: Remove to fresh air and keep at rest in a position comfortable for breathing. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. Immediately call a POISON CENTER or doctor/physician. Call a POISON CENTER or doctor/physician if you feel unwell. If skin irritation occurs: Get medical advice/attention. Take off contaminated clothing and wash before reuse. Dispose of contents/ container to an approved waste disposal plant