1-(n-Butyl)imidazole is used in the synthesis of a heterocyclic mesomeric betaine and 1-(1-butyl-3-imidazolio)propane-3-sulfonate (BIm3S). It acts as an N-coordinated ligand. It is used in the chiral separation of amino acids and anionic pharmaceuticals by capillary electrophoresis. It is used for preparation of substituted phenyl-containing imidazolium ionic liquid.
Nina Gonsior; Fabian Mohr; Helmut Ritter. Synthesis of mesomeric betaine compounds with imidazolium-enolate structure.Beilstein Journal of Organic Chemistry.2012, 8 390-397.
G M Smith; G G Duncan. A study of intravascular platelet aggregation by continuous platelet counting.Thrombosis Research.1981, 23 (3), 275-288.
Preferred ligand in a Cu(I)-catalyzed procedure for cyanation of heteroaryl bromides with potassium hexacyanoferrate(II), as an alternative to conventional routes with highly toxic metal cyanides: Synlett, 555 (2007).
Hazard Statements: H330-H315-H318-H335
Fatal if inhaled. Causes skin irritation. Causes serious eye damage. May cause respiratory irritation.
Precautionary Statements: P260-P304+P340-P305+P351+P338-P320-P405-P501a
Do not breathe dust/fume/gas/mist/vapours/spray. IF INHALED: Remove to fresh air and keep at rest in a position comfortable for breathing. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. Specific treatment is urgent (see label). Store locked up. Dispose of contents/container in accordance with local/regional/national/international regulations.