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1-Cyclohexylpiperidine is used in the preparation of 1-(1-phenylcyclohexyl)piperidine, which shows anticholinesterase activity and antagonistic activity to acetylcholine. It is used as a N-methyl-D-aspartate receptor (NMDAR) antagonist. Further, it is used as an anesthetic for animals.
Orme, C. J.; Wilson, A. D. 1-Cyclohexylpiperidine as a thermolytic draw solute for osmotically driven membrane processes. Desalination 2015, 371, 126-133.
Wilson, A. D.; Orme, C. J. Concentration dependent speciation and mass transport properties of switchable polarity solvents. RSC Adv. 2015, 5 (10), 7740-7751.
Hazard Statements: H315-H319-H335
Causes skin irritation. Causes serious eye irritation. May cause respiratory irritation.
Precautionary Statements: P261-P280a-P305+P351+P338-P304+P340-P405-P501a
Avoid breathing dust/fume/gas/mist/vapours/spray. Wear protective gloves and eye/face protection. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. IF INHALED: Remove to fresh air and keep at rest in a position comfortable for breathing. Store locked up. Dispose of contents/container in accordance with local/regional/national/international regulations.