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L08143 1,2,3,4-Tetrahydroisoquinoline, 97%

CAS Number
91-21-4
Synonyms

Stock No. Size Price ($) Quantity Availability
L08143-14 25g 37.90
L08143-22 100g 108.00
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1,2,3,4-Tetrahydroisoquinoline, 97%

MDL
MFCD00006896
EINECS
202-050-0

Chemical Properties

Formula
C9H11N
Formula Weight
133.19
Melting point
-30°
Boiling Point
232-233°
Flash Point
98°(208°F)
Density
1.049
Refractive Index
1.5680
Storage & Sensitivity
Ambient temperatures.
Solubility
Soluble in water at 20°C 20g/L.

Applications

It is used as a reagent in the preparation of4-(1,2,4-oxadiazol-5-yl)piperidine-1-carboxamides as antiproliferative tubulin inhibitors.

Notes

Store away from oxidizing agents. Keep the container tightly closed and place it in a cool, dry and well ventilated condition. Protect from heat. Keep it refrigerated.

Literature References

Hiroshi Kawai, et al. Novel Endogenous 1,2,3 ,4-Tetrahydroisoquinoline Derivatives: Uptake by Dopamine Transporter and Activity to Induce Parkinsonism.J. Neurochem.,1998,70(2), 745-751.

Estefanía Méndez-Álvarez, et al. Inhibition of brain monoamine oxidase by adducts of 1,2,3,4-tetrahydroisoquinoline with components of cigarette smoke.Life Sci.,1997,60(19), 1719-1727.

GHS Hazard and Precautionary Statements

Hazard Statements: H302+H312+H332-H314

Harmful if swallowed. Harmful in contact with skin. Harmful if inhaled. Causes severe skin burns and eye damage.

Precautionary Statements: P260-P264b-P270-P271-P280-P303+P361+P353-P304+P340-P305+P351+P338-P310-P330-P331-P363-P501c

Do not breathe dust/fume/gas/mist/vapours/spray. Wash face, hands and any exposed skin thoroughly after handling Do not eat, drink or smoke when using this product. Use only outdoors or in a well-ventilated area. Wear protective gloves/protective clothing/eye protection/face protection. IF ON SKIN (or hair): Remove/Take off immediately all contaminated clothing. Rinse skin with water/shower. IF INHALED: Remove to fresh air and keep at rest in a position comfortable for breathing. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. Immediately call a POISON CENTER or doctor/physician. Rinse mouth. Do NOT induce vomiting. Wash contaminated clothing before reuse. Dispose of contents/ container to an approved waste disposal plant

Other References

Beilstein
116156
Hazard Class
8
Packing Group
II
Harmonized Tariff Code
2933.49
TSCA
Yes
RTECS
NX4900000

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