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91-21-4 - 1,2,3,4-Tetrahydroisoquinoline, 97% - L08143 - Alfa Aesar

L08143 1,2,3,4-Tetrahydroisoquinoline, 97%

CAS Number
91-21-4
Synonyms

Size Price ($) Quantity Availability
25g 35.10
100g 99.28
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1,2,3,4-Tetrahydroisoquinoline, 97%

MDL
MFCD00006896
EINECS
202-050-0

Chemical Properties

Formula
C9H11N
Formula Weight
133.19
Melting point
-30°
Boiling Point
232-233°
Flash Point
98°(208°F)
Density
1.049
Refractive Index
1.5680
Solubility
Soluble in water at 20°C 20g/L.

Applications

It is used as a reagent in the preparation of4-(1,2,4-oxadiazol-5-yl)piperidine-1-carboxamides as antiproliferative tubulin inhibitors.

Notes

Store away from oxidizing agents. Keep the container tightly closed and place it in a cool, dry and well ventilated condition. Protect from heat. Keep it refrigerated.

Literature References

Hiroshi Kawai, et al. Novel Endogenous 1,2,3 ,4-Tetrahydroisoquinoline Derivatives: Uptake by Dopamine Transporter and Activity to Induce Parkinsonism.J. Neurochem.,1998,70(2), 745-751.

Estefanía Méndez-Álvarez, et al. Inhibition of brain monoamine oxidase by adducts of 1,2,3,4-tetrahydroisoquinoline with components of cigarette smoke.Life Sci.,1997,60(19), 1719-1727.

GHS Hazard and Precautionary Statements

Hazard Statements: H302-H315-H319-H335

Harmful if swallowed. Causes skin irritation. Causes serious eye irritation. May cause respiratory irritation.

Precautionary Statements: P261-P280-P305+P351+P338-P304+P340-P362-P301+P312-P312-P405-P403+P233-P501a

Avoid breathing dust/fume/gas/mist/vapours/spray. Wear protective gloves/protective clothing/eye protection/face protection. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. IF INHALED: Remove to fresh air and keep at rest in a position comfortable for breathing. Take off contaminated clothing and wash before reuse. IF SWALLOWED: Call a POISON CENTER or doctor/physician if you feel unwell. Store locked up. Store in a well-ventilated place. Keep container tightly closed. Dispose of contents/container in accordance with local/regional/national/international regulations.

Other References

Beilstein
116156
Harmonized Tariff Code
2933.49
TSCA
Yes
RTECS
NX4900000

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