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22232-54-8 - Ethyl 3-methyl-2-thionoimidazoline-1-carboxylate, 97% - Carbimazole - 3-Methyl-2-thionoimidazoline-1-carboxylic acid ethyl ester - L08218 - Alfa Aesar

L08218 Ethyl 3-methyl-2-thionoimidazoline-1-carboxylate, 97%

CAS Number
22232-54-8
Synonyms
Carbimazole
3-Methyl-2-thionoimidazoline-1-carboxylic acid ethyl ester

Size Price ($) Quantity Availability
5g 56.65
25g 150.40
100g 391.20
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Ethyl 3-methyl-2-thionoimidazoline-1-carboxylate, 97%

MDL
MFCD00027421
EINECS
244-854-4

Chemical Properties

Formula
C7H10N2O2S
Formula Weight
186.24
Melting point
122-126°
Sensitivity
Light Sensitive
Solubility
Soluble in water, ethanol, chloroform and acetone. Sightly soluble in water.

Applications

Ethyl 3-methyl-2-thionoimidazoline-1-carboxylate is used as thyroid inhibitor.

Notes

Light sensitive. Keep the container tightly closed in a dry and well-ventilated place.

Literature References

Chernov'yants, M. S.; Dolinkin, A. O.; Chernyshev, A. V.; Khohlov, E. V.; Golovanova, E. G. Interaction of antithyroid drugs with bovine serum albumin: Electrophoretic and fluorimetric study. J. Pharm. Sci. 2010, 99 (3), 1567-1573.

Roy, G.; Das, D.; Mugesh, G. Bioinorganic chemistry aspects of the inhibition of thyroid hormone biosynthesis by anti-hyperthyroid drugs. Inorg. Chim. Acta 2007, 360 (1), 303-316.

GHS Hazard and Precautionary Statements

Hazard Statements: H302-H319-H317

Harmful if swallowed. Causes serious eye irritation. May cause an allergic skin reaction.

Precautionary Statements: P261-P280-P264-P305+P351+P338-P301+P312-P363-P321-P333+P313-P337+P313-P501a

Avoid breathing dust/fume/gas/mist/vapours/spray. Wear protective gloves/protective clothing/eye protection/face protection. Wash thoroughly after handling. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. IF SWALLOWED: Call a POISON CENTER or doctor/physician if you feel unwell. Wash contaminated clothing before reuse. Specific treatment (see label). If skin irritation or rash occurs: Get medical advice/attention. If eye irritation persists: Dispose of contents/container in accordance with local/regional/national/international regulations.

Other References

Merck
14,1798
Beilstein
144339
Harmonized Tariff Code
2933.29
TSCA
No
RTECS
NJ2441000

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