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L08471 N-Benzyloxycarbonyl-L-leucine, 98% (dry wt.), may cont. up to ca 5% solvent

CAS Number
2018-66-8
Synonyms
N-Cbz-L-leucine
Z-Leu-OH

Stock No. Size Price ($) Quantity Availability
L08471-06 5g 24.00
L08471-14 25g 82.60
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N-Benzyloxycarbonyl-L-leucine, 98% (dry wt.), may cont. up to ca 5% solvent

MDL
MFCD00026494
EINECS
217-960-3

Chemical Properties

Formula
C14H19NO4
Formula Weight
265.30
Flash Point
>110°(230°F)
Density
1.00
Refractive Index
1.5080
Storage & Sensitivity
Keep Cold.
Solubility
Not miscible or difficult to mix in water. Soluble in chloroform, DMSO and methanol.

Applications

It is employed as a reactant for peptide-based preparation of potential antitumor agents, preparation of cyclopropyl peptidomimetics and peptide synthesis.

Notes

Store away from oxidizing agents. Keep the container tightly closed and place it in a cool, dry and well ventilated condition. Protect from heat. Keep it refrigerated.

Literature References

Sylvain Aubry, et al. Exploring the potential of the β-thiolactones in bioorganic chemistry.Org. Biomol. Chem.,2011,9(20), 7134-7143.

Norma Dunlap, et al. Three-step synthesis of cyclopropyl peptidomimetics.Org. Lett.,2011,13(18), 4879-4881.

GHS Hazard and Precautionary Statements

Hazard Statements: H315-H320-H335-H361

Causes skin irritation. Causes eye irritation. May cause respiratory irritation. Suspected of damaging fertility or the unborn child.

Precautionary Statements: P201-P202-P261-P264b-P271-P280-P302+P352-P304+P340-P305+P351+P338-P308+P313-P312-P332+P313-P337+P313-P362-P501c

Obtain special instructions before use. Do not handle until all safety precautions have been read and understood. Avoid breathing dust/fume/gas/mist/vapours/spray. Wash face, hands and any exposed skin thoroughly after handling Use only outdoors or in a well-ventilated area. Wear protective gloves/protective clothing/eye protection/face protection. IF ON SKIN: Wash with plenty of soap and water. IF INHALED: Remove to fresh air and keep at rest in a position comfortable for breathing. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. IF exposed or concerned: Get medical advice/attention. Call a POISON CENTER or doctor/physician if you feel unwell. If skin irritation occurs: If eye irritation persists: Take off contaminated clothing and wash before reuse. Dispose of contents/ container to an approved waste disposal plant

Other References

Beilstein
1253861
Harmonized Tariff Code
2924.29
TSCA
No
RTECS
OH2921000

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