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It is employed as a reactant for peptide-based preparation of potential antitumor agents, preparation of cyclopropyl peptidomimetics and peptide synthesis.
Sylvain Aubry, et al. Exploring the potential of the β-thiolactones in bioorganic chemistry.Org. Biomol. Chem.,2011,9(20), 7134-7143.
Norma Dunlap, et al. Three-step synthesis of cyclopropyl peptidomimetics.Org. Lett.,2011,13(18), 4879-4881.
Hazard Statements: H315-H320-H335-H361
Causes skin irritation. Causes eye irritation. May cause respiratory irritation. Suspected of damaging fertility or the unborn child.
Precautionary Statements: P201-P202-P261-P264b-P271-P280-P302+P352-P304+P340-P305+P351+P338-P308+P313-P312-P332+P313-P362-P501c
Obtain special instructions before use. Do not handle until all safety precautions have been read and understood. Avoid breathing dust/fume/gas/mist/vapours/spray. Wash face, hands and any exposed skin thoroughly after handling Use only outdoors or in a well-ventilated area. Wear protective gloves/protective clothing/eye protection/face protection. IF ON SKIN: Wash with plenty of soap and water. IF INHALED: Remove to fresh air and keep at rest in a position comfortable for breathing. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. IF exposed or concerned: Get medical advice/attention. Call a POISON CENTER or doctor/physician if you feel unwell. If skin irritation occurs: Take off contaminated clothing and wash before reuse. Dispose of contents/ container to an approved waste disposal plant