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It can be used to produce 3-(3-dimethylamino-phenyl)-acrylic acid butyl ester at the temperature of 140°C in the presence of reagent Na2CO3 and solvent N,N-dimethyl-acetamide with the reaction time of 20 hours.
John R. Lindsay Smith, et al. Highly selective aromatic chlorinations. Part 2. The chlorination of substituted phenols, anisoles, anilines, and related compounds with N-chloroamines in acidic solution.J. Chem. Soc., Perkin Trans. 2.,1988,3385-391.
Sherif Eldin, et al. Lifetimes of Iminium Ions in Aqueous Solution.J. Am. Chem. Soc.,1995,117(17), 4851-4857.
Hazard Statements: H302-H312-H331
Harmful if swallowed. Harmful in contact with skin. Toxic if inhaled.
Precautionary Statements: P261-P280h-P304+P340-P311a-P405-P501a
Avoid breathing dust/fume/gas/mist/vapours/spray. Wear protective gloves/clothing. IF INHALED: Remove to fresh air and keep at rest in a position comfortable for breathing. Call a POISON CENTER/doctor. Store locked up. Dispose of contents/container in accordance with local/regional/national/international regulations.