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2430-27-5 - 2,2-Di-n-propylacetamide, 97% - Heptane-4-carboxamide - 2-n-Propylpentanamide - L08847 - Alfa Aesar

L08847 2,2-Di-n-propylacetamide, 97%

CAS Number
2430-27-5
Synonyms
Heptane-4-carboxamide
2-n-Propylpentanamide

Size Price ($) Quantity Availability
5g 85.18
25g 220.80
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2,2-Di-n-propylacetamide, 97%

MDL
MFCD00051534
EINECS
219-394-2

Chemical Properties

Formula
C8H17NO
Formula Weight
143.23
Melting point
123-127°
Solubility
Soluble in chloroform, dimethyl sulfoxide and methanol. Insoluble in water.

Applications

It is employed as an antiepileptic drug. It is hydrolyzed quickly to VPA in vivo, but has intrinsic anticonvulsant activity. Also a reactant used in the synthesis of mutual prodrugs containing bio-cleavable and drug releasable disulfide linkers.

Notes

Store in cool. Keep container tightly closed in a dry and well-ventilated place. Store away from oxidizing agent.

Literature References

Ilan Winkler; Simcha Blotnik; Jakob Shimshoni; Boris Yagen; Marshall Devor; Meir Bialer. Efficacy of antiepileptic isomers of valproic acid and valpromide in a rat model of neuropathic pain. British Journal of Pharmacology. 2005, 146 (2), 198-208.

Galit Shaltiel et. al. Valproate decreases inositol biosynthesis. Biological Psychiatry. 2004, 56(11), 868-874.

GHS Hazard and Precautionary Statements

Hazard Statements: H302

Harmful if swallowed.

Precautionary Statements: P264-P270-P301+P312-P330-P501a

Wash thoroughly after handling. Do not eat, drink or smoke when using this product. IF SWALLOWED: Call a POISON CENTER or doctor/physician if you feel unwell. Rinse mouth. Dispose of contents/container in accordance with local/regional/national/international regulations.

Other References

Merck
14,9914
Beilstein
1750444
Harmonized Tariff Code
2924.19
TSCA
No
RTECS
YV5965500

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