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1,4-Bis(trimethylsilyl)-1,3-butadiyne is used in Negishi protocol for the synthesis of glycosylated oligo(ethynylene)s. It is also used as pharmaceutical intermediates.
Tobias N Hoheisel; Holger Frauenrath. A convenient Negishi protocol for the synthesis of glycosylated oligo(ethynylene)s.Organic Letters.2008, 10 (20), 4525-4528.
Tetsuo Kusumoto; Tamejiro Hiyama. Hydrosilylation of 1,4-Bis(Trimethylsilyl)-1,3-Butadiyne. Chemistry Letters.1985, 14 (9), 1405-1408.
Hazard Statements: H228
Precautionary Statements: P210-P280a-P240-P241-P370+P378a
Keep away from heat/sparks/open flames/hot surfaces. - No smoking. Wear protective gloves and eye/face protection. Ground/bond container and receiving equipment. Use explosion-proof electrical/ventilating/lighting/ equipment. In case of fire: Use for extinction: CO2, powder or water spray.