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39098-97-0 - 2-Thiopheneacetyl chloride, 98% - 2-Thienylacetyl chloride - L09323 - Alfa Aesar

L09323 2-Thiopheneacetyl chloride, 98%

CAS Number
39098-97-0
Synonyms
2-Thienylacetyl chloride

Size Price ($) Quantity Availability
25g 67.20
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2-Thiopheneacetyl chloride, 98%

MDL
MFCD00005456
EINECS
254-290-0

Chemical Properties

Formula
C6H5ClOS
Formula Weight
160.62
Boiling Point
131-132°/90mm
Flash Point
101°(213°F)
Density
1.303
Refractive Index
1.5513
Sensitivity
Moisture Sensitive
Solubility
Reacts with water.

Applications

2-Thiopheneacetyl chloride was used in the synthesis of (S)-ethyl-1-(2-thiopheneacetyl)-3-piperidinecarboxylate, nipecotate-containing immunopotentiator, 5-fluorouracil-cephalosporin prodrug, series of new N,N?-di(thiopheneacetyl)diamines derivatives and 6-β-(thiophen-2?-yl)acetamidomorphine. Also used in the synthesis of Nitrocefin.

Notes

Moisture Sensitive, store away from moisture. Store in cool. Keep container tightly closed in a dry and well-ventilated place. Store away from oxidizing agent.

Literature References

Moher ED, et al. Development of an efficient synthesis for a nipecotate-containing immunopotentiator. Org. Process Res. Dev,2004, 8 (4), 593-6.

Ryan M Phelan; Marc Ostermeier; Craig A Townsend; Ryan M. Phelan; Marc Ostermeier; Craig A. Townsend. Design and synthesis of a beta-lactamase activated 5-fluorouracil prodrug. Bioorganic & Medicinal Chemistry Letters,2009, 19(4), 1261-1263.

GHS Hazard and Precautionary Statements

Hazard Statements: H302-H314-H318

Harmful if swallowed. Causes severe skin burns and eye damage. Causes serious eye damage.

Precautionary Statements: P260u-P303+P361+P353-P305+P351+P338-P301+P330+P331-P405-P501a

IF ON SKIN (or hair): Remove/Take off immediately all contaminated clothing. Rinse skin with water/shower. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. IF SWALLOWED: Rinse mouth. Do NOT induce vomiting. Store locked up. Dispose of contents/container in accordance with local/regional/national/international regulations.

Other References

Beilstein
114547
Hazard Class
8
Packing Group
II
Harmonized Tariff Code
2934.99
TSCA
Yes

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