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29617-66-1 - (S)-(-)-2-Chloropropionic acid, 99% - L09427 - Alfa Aesar

L09427 (S)-(-)-2-Chloropropionic acid, 99%

CAS Number
29617-66-1
Synonyms

Size Price ($) Quantity Availability
5g 50.90
25g 153.00
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(S)-(-)-2-Chloropropionic acid, 99%

MDL
MFCD00064205
EINECS
411-150-5

Chemical Properties

Formula
C3H5ClO2
Formula Weight
108.53
Melting point
Boiling Point
187°
Flash Point
107°(225°F)
Density
1.270
Refractive Index
1.4345
Solubility
Fully miscible in water.

Applications

Through the stereo displacement of (S)-(-)-2-Chloropropionic acid PPAR Agonist can be synthesized via asymmetric hydrogenation of a cinnamic acid derivative.

Notes

Store in cool dry condition. Incompatible with strong oxidizing agents.

Literature References

Ioannis N. Houpis.; Lawrence E. Patterson.; Charles A. Alt.; John R. Rizzo.; Tony Y. Zhang.; Michael Haurez. Synthesis of PPAR Agonist via Asymmetric Hydrogenation of a Cinnamic Acid Derivative and Stereospecific Displacement of (S)-2-Chloropropionic Acid.Org. Lett. 2005, 7 (10),1947-1950 .

Atsushi Kurata.; Tatsuo Kurihara.; Harumi Kamachi.; Nobuyoshi Esaki. Asymmetric reduction of 2-chloroacrylic acid to (S)-2-chloropropionic acid by a novel reductase from Burkholderia sp. WSTetrahedron: Asymmetry. 2004, 15 (18),2837-2839 .

GHS Hazard and Precautionary Statements

Hazard Statements: H314-H318-H302-H312

Causes severe skin burns and eye damage. Causes serious eye damage. Harmful if swallowed. Harmful in contact with skin.

Precautionary Statements: P260-P280-P303+P361+P353-P305+P351+P338-P301+P330+P331-P304+P340-P310-P301+P312-P405-P501a

Do not breathe dust/fume/gas/mist/vapours/spray. Wear protective gloves/protective clothing/eye protection/face protection. IF ON SKIN (or hair): Remove/Take off immediately all contaminated clothing. Rinse skin with water/shower. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. IF SWALLOWED: Rinse mouth. Do NOT induce vomiting. IF INHALED: Remove to fresh air and keep at rest in a position comfortable for breathing. Immediately call a POISON CENTER or doctor/physician. Call a POISON CENTER or doctor/physician if you feel unwell. Store locked up. Dispose of contents/container in accordance with local/regional/national/international regulations.

Other References

Beilstein
1720257
Hazard Class
8
Packing Group
III
Harmonized Tariff Code
2915.90
TSCA
No
RTECS
UA2451950

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