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4-Amino-3-nitrophenol was used in the synthesis of benzimidazole based Factor Xa (trypsin-like serine protease) inhibitors and 4-(4-amino-3-nitrophenoxy)phthalonitrile. It was also employed as matrix during visible matrix-assisted laser desorption/ionization mass spectrometry.
Rosa Blanco.; Belén de la Hoz.; Concepción Sánchez-Fernández.; Moisés Sánchez-Cano. Allergy to 4-amino-3-nitrophenol in a hair dye.Contact Dermatitis. 1998, 39 (3),136 .
Hazard Statements: H302-H312-H319
Harmful if swallowed. Harmful in contact with skin. Causes serious eye irritation.
Precautionary Statements: P280h-P305+P351+P338
Wear protective gloves/clothing. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.