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4,4,4-Trifluoro-3-hydroxy-3-(trifluoromethyl)butyric acid is a beta-hydroxy acid undergoes cyclization reaction to prepare beta-lactone.
Schalekamp, H.; Hosten, E. C.; Betz, R. Redetermination of the crystal structure of endo-2-carboxy-bicyclo[2.2.1]- heptane, C8H12O2. Z. Kristallogr. - New Cryst. Struct. 2015, 230 (1), 33-34.
Weidler-Kubanek, A. M.; Litt, M. H. Addition of hexafluoroacetone to ketenimines. J. Org. Chem. 1968, 33 (5), 1844-1846.
Hazard Statements: H302-H314-H318
Harmful if swallowed. Causes severe skin burns and eye damage. Causes serious eye damage.
Precautionary Statements: P280-P305+P351+P338-P301+P330+P331-P501a
Wear protective gloves/protective clothing/eye protection/face protection. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. IF SWALLOWED: Rinse mouth. Do NOT induce vomiting. Dispose of contents/container in accordance with local/regional/national/international regulations.