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3,5-Bis(trifluoromethyl)phenyl isocyanate is used in Chemical derivatization of amino-functionalized model surfaces. Preparation of arylaminothiocarbonylpyridinium zwitterionic salts, via an exothermic reaction with 4-pyrrolidinopyridine. Synthesis of (S)-3-hydroxymethyl-2-methoxymethoxy-2?-(3-(3,5-bis(trifluoromethyl)phenyl)uryl-benzyl)-1,10-binaphthalene. Synthesis of 1-[3,5-bis(trifluoromethyl) phenyl]-3-(2-pyridyl)thiourea, via reaction with 2-amino pyridine in MeCN.
Nora Graf; Andreas Lippitz; Thomas Gross; Falko Pippig; Andreas Holländer; Wolfgang E S Unger. Determination of accessible amino groups on surfaces by chemical derivatization with 3,5-bis(trifluoromethyl)phenyl isothiocyanate and XPS/NEXAFS analysis.Analytical and Bioanalytical Chemistry.2010, 396 (2), 725-738.
Kazuaki Ishihara; Masatoshi Niwa; Yuji Kosugi. Zwitterionic salts as mild organocatalysts for transesterification.Organic Letters.2008, 10 (11), 2187-2190.
Hazard Statements: H227-H302-H331-H315-H319-H334-H335
Combustible liquid. Harmful if swallowed. Toxic if inhaled. Causes skin irritation. Causes serious eye irritation. May cause allergy or asthma symptoms or breathing difficulties if inhaled. May cause respiratory irritation.
Precautionary Statements: P260-P201-P280h-P304+P340-P405-P501a
Do not breathe dust/fume/gas/mist/vapours/spray. Obtain special instructions before use. Wear protective gloves/clothing. IF INHALED: Remove to fresh air and keep at rest in a position comfortable for breathing. Store locked up. Dispose of contents/container in accordance with local/regional/national/international regulations.