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5267-64-1 - D-Phenylalaninol, 98% - (R)-(+)-2-Amino-3-phenyl-1-propanol - H-D-Phe-ol - L09697 - Alfa Aesar

L09697 D-Phenylalaninol, 98%

CAS Number
5267-64-1
Synonyms
(R)-(+)-2-Amino-3-phenyl-1-propanol
H-D-Phe-ol

Size Price ($) Quantity Availability
250mg 22.30
1g 42.70
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D-Phenylalaninol, 98%

MDL
MFCD00064298
EINECS
226-086-1

Chemical Properties

Formula
C9H13NO
Formula Weight
151.21
Melting point
89-94°
Sensitivity
Air Sensitive
Solubility
Soluble in Dichloromethane, Ethyl Acetate, Methanol.

Applications

D-Phenylalaninol is used as a chiral auxiliary for asymmetric Michael reactions. It is an enantiomer of L-Phenylalaninol, an inhibitor of intestinal Phenylalanine absorption. It acts as an inhibiting agent to the enzymes which are responsible for the breakdown of endorphins.

Notes

Air Sensitive. Store away from air. Store under dry inert gas. Incompatible with carbondioxide, air, acids and oxidizing agents.

Literature References

W W Mak; J T Wong. Relationship between membrane fluidity and capping of receptors for concanavalin A.Canadian journal of biochemistry.1980, 58 (12), 1421-1429.

W W Mak; L Pinteric; J T Wong. Enhanced sensitivity of tumorigenic cells to rapid rounding induced by phenylalaninol.Canadian journal of biochemistry.1980, 58 (9), 737-744.

Has been used as a chiral auxiliary for asymmetric Michael reactions: J. Org. Chem., 50, 3863 (1985).

GHS Hazard and Precautionary Statements

Hazard Statements: H314-H318

Causes severe skin burns and eye damage. Causes serious eye damage.

Precautionary Statements: P280-P303+P361+P353-P305+P351+P338-P310

Wear protective gloves/protective clothing/eye protection/face protection. IF ON SKIN (or hair): Remove/Take off immediately all contaminated clothing. Rinse skin with water/shower. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. Immediately call a POISON CENTER or doctor/physician.

Other References

Beilstein
4665408
Hazard Class
8
Packing Group
III
Harmonized Tariff Code
2922.19
TSCA
No

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