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D-Phenylalaninol is used as a chiral auxiliary for asymmetric Michael reactions. It is an enantiomer of L-Phenylalaninol, an inhibitor of intestinal Phenylalanine absorption. It acts as an inhibiting agent to the enzymes which are responsible for the breakdown of endorphins.
W W Mak; J T Wong. Relationship between membrane fluidity and capping of receptors for concanavalin A.Canadian journal of biochemistry.1980, 58 (12), 1421-1429.
W W Mak; L Pinteric; J T Wong. Enhanced sensitivity of tumorigenic cells to rapid rounding induced by phenylalaninol.Canadian journal of biochemistry.1980, 58 (9), 737-744.
Has been used as a chiral auxiliary for asymmetric Michael reactions: J. Org. Chem., 50, 3863 (1985).
Hazard Statements: H314-H318
Causes severe skin burns and eye damage. Causes serious eye damage.
Precautionary Statements: P280-P303+P361+P353-P305+P351+P338-P310a
Wear protective gloves/protective clothing/eye protection/face protection. IF ON SKIN (or hair): Remove/Take off immediately all contaminated clothing. Rinse skin with water/shower. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.