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L09834 4',5,7-Trihydroxyflavanone, 97%

CAS Number
67604-48-2
Synonyms
Naringenin

Stock No. Size Price ($) Quantity Availability
L09834-04 2g 27.70
L09834-09 10g 71.80
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4',5,7-Trihydroxyflavanone, 97%

MDL
MFCD00006844
EINECS
266-769-1

Chemical Properties

Formula
C15H12O5
Formula Weight
272.26
Melting point
248-251°
Storage & Sensitivity
Ambient temperatures.
Solubility
Soluble in ethanol (50 mg/ml), DMSO, methanol, and ammonium hydroxide (50 mg/ml). Insoluble in water (almost)

Applications

(±)-Naringenin is an antioxidant flavonoid. It has anti-inflammatory and antitumor properties. (±)-Naringenin induces apoptosis. It stimulates DNA repair following oxidative damage. (±)-Naringenin inhibits the activity of PI 3-kinase (PI(3)K).

Notes

Store at room temperature. Incompatible with strong oxidizing agents.

Literature References

J. Foyere Ayafor.; Joseph D. Connolly. 2R,3R-(+)-3-acetoxy-4?,5-dihydroxy-7-methoxyflavanone and 2R,3R-(+)-3-acetoxy-4?,5,7-trihydroxyflavanone: two new 3-acetylated dihydroflavonols from Aframomum pruinosum Gagnepain (Zingiberaceae).J. Chem. Soc., Perkin Trans. 1. 1981, ,2563-2565 .

GHS Hazard and Precautionary Statements

Hazard Statements: H315-H319-H335

Causes skin irritation. Causes serious eye irritation. May cause respiratory irritation.

Precautionary Statements: P261-P264b-P271-P280-P302+P352-P304+P340-P305+P351+P338-P312-P332+P313-P337+P313-P362-P501c

Avoid breathing dust/fume/gas/mist/vapours/spray. Wash face, hands and any exposed skin thoroughly after handling Use only outdoors or in a well-ventilated area. Wear protective gloves/protective clothing/eye protection/face protection. IF ON SKIN: Wash with plenty of soap and water. IF INHALED: Remove to fresh air and keep at rest in a position comfortable for breathing. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. Call a POISON CENTER or doctor/physician if you feel unwell. If skin irritation occurs: Get medical advice/attention. If eye irritation persists: Take off contaminated clothing and wash before reuse. Dispose of contents/ container to an approved waste disposal plant

Other References

Merck
14,6424
Harmonized Tariff Code
2932.99
TSCA
No
RTECS
DJ2981530

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