I agree Our site saves small pieces of text information (cookies) on your device in order to deliver better content and for statistical purposes. You can disable the usage of cookies by changing the settings of your browser. By browsing our website without changing the browser settings you grant us permission to store that information on your device.
1-Bromo-1-chloro-2,2,2-trifluoroethane has been used in a study that combined molecular simulations with free energy simulations to study solvation of halothane in polarizable water and methanol. It is also used in a study to investigate the interaction of anesthetics with the Rho GTPase regulator Rho GDP dissociation inhibitor. In an effect believed to be independent of anesthesia, halothane inhibits synthesis of 5-hydroxytryptamine in brain tissue, probably at the tryptophan hydroxylase step.
S Bourgoin; J P Ternaux; A Boireau; F Héry; M Hamon. Effects of halothane and nitrous oxide anesthesia on 5-HT turn-over in the rat brain.Naunyn-Schmiedebergs Archives of Pharmacology.1975, 288 (2-3), 109-121.
Travis J A Craddock; Marc St George; Holly Freedman; Khaled H Barakat; Sambasivarao Damaraju; Stuart Hameroff; Jack A Tuszynski. Computational predictions of volatile anesthetic interactions with the microtubule cytoskeleton: implications for side effects of general anesthesia.PLoS ONE.2012, 7 (6), e37251.
Hazard Statements: H318-H341
Causes serious eye damage. Suspected of causing genetic defects.
Precautionary Statements: P260-P201-P280i-P304+P340-P405-P501a
Do not breathe dust/fume/gas/mist/vapours/spray. Obtain special instructions before use. Wear eye/face protection. IF INHALED: Remove to fresh air and keep at rest in a position comfortable for breathing. Store locked up. Dispose of contents/container in accordance with local/regional/national/international regulations.