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(R)-1-phenylethyl isocyanate is used in the derivatisation of alcohols, thiocarbamates and hydroxy fatty acids. (R)-1-phenylethyl isocyanate moderately inhibited both BP-DNA adducts.
Andreas Habel,; Dieter Spiteller,; Wilhelm Boland .1-Phenylethyl isocyanate is a powerful reagent for the chiral analysis of secondary alcohols and hydroxy fatty acids with remote stereogenic centres. Journal of Chromatography A. 2007, 1165 (1-2), 182-190.
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Reagent for determination of chiral purity of alcohols and amines: Anal. Lett., 3, 323 (1970).
Hazard Statements: H227-H302-H331-H315-H319-H334-H335
Combustible liquid. Harmful if swallowed. Toxic if inhaled. Causes skin irritation. Causes serious eye irritation. May cause allergy or asthma symptoms or breathing difficulties if inhaled. May cause respiratory irritation.
Precautionary Statements: P260-P280h-P305+P351+P338-P309-P310a
Do not breathe dust/fume/gas/mist/vapours/spray. Wear protective gloves/clothing. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. IF exposed or if you feel unwell: