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L10572 4-Phenoxyphenylacetonitrile, 98%

CAS Number
92163-15-0
Synonyms
4-Phenoxybenzyl cyanide

Stock No. Size Price ($) Quantity Availability
L10572-03 1g 55.30
L10572-06 5g 184.00
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4-Phenoxyphenylacetonitrile, 98%

MDL
MFCD00016399

Chemical Properties

Formula
C14H11NO
Formula Weight
209.25
Boiling Point
145°/1mm
Density
1.120
Refractive Index
1.5820
Storage & Sensitivity
Ambient temperatures.
Solubility
Miscible with toluene.

Applications

4-Phenoxyphenylacetonitrile is involved in the preparation of 2-(4-phenoxybenzoyl)-5-hydroxyindole, which is used as aCa2+/calmodulin-dependent protein kinase II (CaMKII) inhibitor.

Notes

Incompatible with oxidizing agents.

Literature References

Komiya, M.; Asano, S.; Koike, N.; Koga, E.; Igarashi, J.; Nakatani, S.; Isobe, Y. Synthesis of Novel Benzo-Fused Heteroaryl Derivatives as Ca2+/Calmodulin-Dependent Protein Kinase II Inhibitors. Chem. Pharm. Bull. 2013, 61 (10), 1094-1097.

Azam, F.; Prasad, M. V. V.; Thangavel, N. Structure-based design, synthesis, and molecular modeling studies of 1-(benzo[d]thiazol-2-yl)-3-(substituted aryl)urea derivatives as novel anti-Parkinsonian agents. Med. Chem. Res. 2012, 21 (9), 2630-2643.

GHS Hazard and Precautionary Statements

Hazard Statements: H302

Harmful if swallowed.

Precautionary Statements: P280f

Wear protective clothing.

Other References

Beilstein
2693571
Harmonized Tariff Code
2926.90
TSCA
No

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