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L10579 1-Phenylimidazole, 99%

CAS Number
7164-98-9
Synonyms

Stock No. Size Price ($) Quantity Availability
L10579-MD 250mg 22.10
L10579-03 1g 57.90
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1-Phenylimidazole, 99%

MDL
MFCD00041204

Chemical Properties

Formula
C9H8N2
Formula Weight
144.18
Melting point
13°
Boiling Point
142°/15mm
Flash Point
>110°(230°F)
Density
1.140
Refractive Index
1.6000
Storage & Sensitivity
Ambient temperatures.
Solubility
Slightly soluble in water.

Applications

1-phenylimidazole is a ligand for cytochrome P-450 and used as an inhibitor of microsomal oxidation. 1-Phenylimidazole is a suitable reagent used to investigate its effect on the citrulline formation by bovine brain nitric-oxide synthase. 1-Phenylimidazole is reported to be inhibitor of calmodulin-dependent nitric-oxide synthase from bovine brain and GHs pituitary cells.

Notes

Store in cool place. Keep container tightly closed in a dry and well-ventilated place. Store away from strong oxidizing agents.

Literature References

Christopher F. Wilkinson,; Krystyna Hetnarski,; Michael S. Denison. Selectivity of 1-phenylimidazole as a ligand for cytochrome P-450 and as an inhibitor of microsomal oxidation. Biochemical Pharmacology. 1983, 32 (6) 997-1003.

Sarvesh C. Vashishtha,; Edward M. Hawes,; Gordon McKay,; Denis J. McCann. Synthesis and Identification of the Quaternary Ammonium-Linked Glucuronide of 1-Phenylimidazole in Human Liver Microsomes and Investigation of the Human UDP-Glucuronosyltransferases Involved. Drud metabolism and disposition. 2000, 28 (9), 1009-1013.

GHS Hazard and Precautionary Statements

Hazard Statements: H315-H319-H335

Causes skin irritation. Causes serious eye irritation. May cause respiratory irritation.

Precautionary Statements: P261-P264b-P271-P280-P302+P352-P304+P340-P305+P351+P338-P312-P332+P313-P337+P313-P362-P501c

Avoid breathing dust/fume/gas/mist/vapours/spray. Wash face, hands and any exposed skin thoroughly after handling Use only outdoors or in a well-ventilated area. Wear protective gloves/protective clothing/eye protection/face protection. IF ON SKIN: Wash with plenty of soap and water. IF INHALED: Remove to fresh air and keep at rest in a position comfortable for breathing. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. Call a POISON CENTER or doctor/physician if you feel unwell. If skin irritation occurs: Get medical advice/attention. If eye irritation persists: Take off contaminated clothing and wash before reuse. Dispose of contents/ container to an approved waste disposal plant

Other References

Beilstein
112356
Harmonized Tariff Code
2933.29
TSCA
No

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