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2-(Trifluoromethyl)phenyl isocyanate is an important raw material and intermediate used in organic synthesis, pharmaceuticals, agrochemicals and dyestuff fields.
Kevin G Liu.; Millard H Lambert.; Lisa M Leesnitzer.; William Oliver Jr.; Ronda J Ott.; Kelli D Plunket.; Ludwig W Stuart.; Peter J Brown.; Timothy M Willson.; Daniel D Sternbach. Identification of a series of PPARγ/δ dual agonists via solid-Phase parallel synthesis. Bioorganic & Medicinal Chemistry Letters. 2001, 11 (22), 2959-2962.
Zhaoguang Li.; He Huang.; Hongbin Sun.; Hualiang Jiang.; Hong Liu. Microwave-Assisted Efficient and Convenient Synthesis of 2,4(1H,3H)-Quinazolinediones and 2-Thioxoquinazolines. J. Comb. Chem. 2008, 10 (3), 484-486.
Hazard Statements: H226-H312-H315-H319-H330-H334-H335
Flammable liquid and vapour. Harmful in contact with skin. Causes skin irritation. Causes serious eye irritation. Fatal if inhaled. May cause allergy or asthma symptoms or breathing difficulties if inhaled. May cause respiratory irritation.
Precautionary Statements: P210-P233-P235-P240-P241-P242-P243-P260-P264b-P271-P280-P284-P285-P303+P361+P353-P304+P340-P305+P351+P338-P310-P312-P332+P313-P337+P313-P363-P370+P378q-P501c
Keep away from heat/sparks/open flames/hot surfaces. - No smoking. Keep container tightly closed. Keep cool. Ground/bond container and receiving equipment. Use explosion-proof electrical/ventilating/lighting/ equipment. Use only non-sparking tools. Take precautionary measures against static discharge. Do not breathe dust/fume/gas/mist/vapours/spray. Wash face, hands and any exposed skin thoroughly after handling Use only outdoors or in a well-ventilated area. Wear protective gloves/protective clothing/eye protection/face protection. Wear respiratory protection. In case of inadequate ventilation wear respiratory protection. IF ON SKIN (or hair): Remove/Take off immediately all contaminated clothing. Rinse skin with water/shower. IF INHALED: Remove to fresh air and keep at rest in a position comfortable for breathing. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. Immediately call a POISON CENTER or doctor/physician. Call a POISON CENTER or doctor/physician if you feel unwell. If skin irritation occurs: Get medical advice/attention. If eye irritation persists: Wash contaminated clothing before reuse. In case of fire: Use CO2, dry chemical, or foam Dispose of contents/ container to an approved waste disposal plant