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3,5-Dimethylphenyl isocyanate is applications include linking with oligosaccharides and cyclodextrins for chiral chromatography stationary phases.
Tihamer Hargitai.; Yoshio Okamoto. Evaluation of 3,5-Dimethylphenyl Carbamoylated α-, β-, and γ-Cyclodextrins as Chiral Stationary Phases for HPLC. Journal of Liquid Chromatography. 1993, 16 (4), 843-858.
Pilar Franco.; Antonio Senso.; Cristina Minguillón.; Laureano Oliveros. 3,5-Dimethylphenylcarbamates of amylose, chitosan and cellulose bonded on silica gel: Comparison of their chiral recognition abilities as high-performance liquid chromatography chiral stationary phases. Journal of Chromatography A. 1998, 796 (2), 265-272.
Reaction with oligosaccharides and cyclodextrins gives 3,5-dimethylcarbamates which have been evaluated as chiral stationary phases for HPLC: J. Chromat., 628, 11 (1993); Bull. Chem. Soc. Jpn., 63, 3606 (1990).
Hazard Statements: H227-H302-H312-H315-H319-H332-H334-H335
Combustible liquid. Harmful if swallowed. Harmful in contact with skin. Causes skin irritation. Causes serious eye irritation. Harmful if inhaled. May cause allergy or asthma symptoms or breathing difficulties if inhaled. May cause respiratory irritation.
Precautionary Statements: P210-P235-P261-P264b-P270-P271-P280-P285-P301+P312-P302+P352-P304+P340-P305+P351+P338-P312-P330-P332+P313-P337+P313-P342+P311-P362-P370+P378q-P501c
Keep away from heat/sparks/open flames/hot surfaces. - No smoking. Keep cool. Avoid breathing dust/fume/gas/mist/vapours/spray. Wash face, hands and any exposed skin thoroughly after handling Do not eat, drink or smoke when using this product. Use only outdoors or in a well-ventilated area. Wear protective gloves/protective clothing/eye protection/face protection. In case of inadequate ventilation wear respiratory protection. IF SWALLOWED: Call a POISON CENTER or doctor/physician if you feel unwell. IF ON SKIN: Wash with plenty of soap and water. IF INHALED: Remove to fresh air and keep at rest in a position comfortable for breathing. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. Rinse mouth. If skin irritation occurs: Get medical advice/attention. If eye irritation persists: If experiencing respiratory symptoms: Call a POISON CENTER or doctor/physician. Take off contaminated clothing and wash before reuse. In case of fire: Use CO2, dry chemical, or foam Dispose of contents/ container to an approved waste disposal plant