3,5-Dimethylphenyl isocyanate is applications include linking with oligosaccharides and cyclodextrins for chiral chromatography stationary phases.
Tihamer Hargitai.; Yoshio Okamoto. Evaluation of 3,5-Dimethylphenyl Carbamoylated α-, β-, and γ-Cyclodextrins as Chiral Stationary Phases for HPLC. Journal of Liquid Chromatography. 1993, 16 (4), 843-858.
Pilar Franco.; Antonio Senso.; Cristina Minguillón.; Laureano Oliveros. 3,5-Dimethylphenylcarbamates of amylose, chitosan and cellulose bonded on silica gel: Comparison of their chiral recognition abilities as high-performance liquid chromatography chiral stationary phases. Journal of Chromatography A. 1998, 796 (2), 265-272.
Reaction with oligosaccharides and cyclodextrins gives 3,5-dimethylcarbamates which have been evaluated as chiral stationary phases for HPLC: J. Chromat., 628, 11 (1993); Bull. Chem. Soc. Jpn., 63, 3606 (1990).
Hazard Statements: H227-H300-H330-H315-H319-H334-H335
Combustible liquid. Fatal if swallowed. Fatal if inhaled. Causes skin irritation. Causes serious eye irritation. May cause allergy or asthma symptoms or breathing difficulties if inhaled. May cause respiratory irritation.
Precautionary Statements: P301+P310a-P304+P340-P305+P351+P338-P320-P330-P405-P501a
IF SWALLOWED: Immediately call a POISON CENTER/doctor IF INHALED: Remove to fresh air and keep at rest in a position comfortable for breathing. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. Specific treatment is urgent (see label). Rinse mouth. Store locked up. Dispose of contents/container in accordance with local/regional/national/international regulations.