Cookies disclaimer

I agree Our site saves small pieces of text information (cookies) on your device in order to deliver better content and for statistical purposes. You can disable the usage of cookies by changing the settings of your browser. By browsing our website without changing the browser settings you grant us permission to store that information on your device.

L11939 Thiazolyl Blue tetrazolium bromide, 98%

CAS Number
298-93-1
Synonyms
3-(4,5-Dimethyl-2-thiazolyl)-2,5-diphenyl-2H-tetrazolium bromide
MTT

Stock No. Size Price ($) Quantity Availability
L11939-03 1g 46.90
L11939-06 5g 144.00
Add to Cart Bulk/Specialty Print Quote View Item

Thiazolyl Blue tetrazolium bromide, 98%

MDL
MFCD00011964
EINECS
206-069-5

Chemical Properties

Formula
C18H16BrN5S
Formula Weight
414.33
Melting point
ca 195° dec.
Storage & Sensitivity
Moisture Sensitive. Air Sensitive. Light Sensitive. Store under Nitrogen. Ambient temperatures.
Solubility
Soluble in water, ethanol, 2-methoxyethanol and phosphate buffered saline.

Applications

Used in measurement of cell proliferation. Produces a yellowish solution that is converted to dark blue, water-insoluble MTT formazan by mitochondrial dehydrogenases of living cells.Thiazolyl Blue tetrazolium bromide is a dye used in measurement of cell proliferation. It is used as a direct indicator of cytotoxicity (such as for screening cancer drugs) and apoptosis. As an electron acceptor, it is utilized for studying nicotinamide adenine dinucleotide phosphate (NADP)-dependent dehydrogenases.

Notes

Light, air and moisture sensitive. Store in a cool place. Keep the container tightly closed in a dry and well-ventilated place. Incompatible with strong oxidizing agents.

Literature References

Ma, W.; Xu, A.; Ying, J.; Li, B.; Jin, Y. Biodegradable Core-Shell Copolymer-Phospholipid Nanoparticles for Combination Chemotherapy: An In Vitro Study. J. Biomed. Nanotechnol. 2015, 11 (7), 1193-1200.

Wei, D.; Chen, T.; Yan, M.; Zhao, W.; Li, F.; Cheng, W.; Yuan, L. Synthesis, characterization, antioxidant activity and neuroprotective effects of selenium polysaccharide from Radix hedysari. Carbohydr. Polym. 2015, 125, 161-168.

GHS Hazard and Precautionary Statements

Hazard Statements: H315-H319-H335-H341

Causes skin irritation. Causes serious eye irritation. May cause respiratory irritation. Suspected of causing genetic defects.

Precautionary Statements: P201-P202-P261-P264b-P271-P280i-P281-P302+P352-P304+P340-P305+P351+P338-P308+P313-P332+P313-P337+P313-P362-P501c

Obtain special instructions before use. Do not handle until all safety precautions have been read and understood. Avoid breathing dust/fume/gas/mist/vapours/spray. Wash face, hands and any exposed skin thoroughly after handling Use only outdoors or in a well-ventilated area. Wear eye/face protection. Use personal protective equipment as required. IF ON SKIN: Wash with plenty of soap and water. IF INHALED: Remove to fresh air and keep at rest in a position comfortable for breathing. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. IF exposed or concerned: Get medical advice/attention. If skin irritation occurs: If eye irritation persists: Take off contaminated clothing and wash before reuse. Dispose of contents/ container to an approved waste disposal plant

Other References

Beilstein
3825277
Harmonized Tariff Code
2934.99
TSCA
Yes
RTECS
XF8060000

Recommended

  • A13280

    Dimethyl sulfoxide, 99+%
  • A14965

    Tetraethoxysilane, 98%
  • A15029

    1-Chloronaphthalene, tech. 85%, remainder 2-chloronaphthalene
  • A18836

    Amidosulfonic acid, 98+%
  • L05316

    3-Aminocrotononitrile, (E)+(Z), 96%

Recently Viewed

Chemicals

Life Science

Metals & Materials

Catalysts

Analytical & Labware