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1338-39-2 - Sorbitan monolaurate - Sorbitan monododecanoate - Span® 20 - L12099 - Alfa Aesar

L12099 Sorbitan monolaurate

CAS Number
1338-39-2
Synonyms
Sorbitan monododecanoate
Span® 20

Size Price ($) Quantity Availability
250g 26.90
1000g 71.40
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Sorbitan monolaurate

MDL
MFCD00005365
EINECS
215-663-3

Chemical Properties

Formula
C18H34O6
Formula Weight
346.47
Flash Point
>110°(230°F)
Density
1.032
Refractive Index
1.4740
Solubility
Soluble in 2-ethoxyethanol, ethanol and methanol. Not miscible or difficult to mix in water.

Applications

Sorbitan monolaurate is a detergent and monoester of lauric acid and hexitol anhydrides derived from sorbitol. It is used in a study to assess enhanced solubility and oral bioavailability of itraconazole. It is also used in a study to investigate the oxidation of unsaturated lipids in oil-in-water emulsions.

Notes

Store in cool place. Keep container tightly closed in a dry and well-ventilated place. Incompatible with strong oxidizing agents.

Literature References

Claire Berton.; Claude Genot.; Dominique Guibert.; Marie-Hélène Ropers.; Claire Berton.; Claude Genot, Dominique Guibert.; Marie-Hélène Ropers. Effect of lateral heterogeneity in mixed surfactant-stabilized interfaces on the oxidation of unsaturated lipids in oil-in-water emulsions. Journal of Colloid and Interface Science. 2012, 377 (1), 244-250.

Young Keun Choi.; Bijay K. Poudel.; Nirmal Marasini.; Kwan Yeol Yang.; Jeong Whan Kim.; Jong Oh Kim.; Han-Gon Choi.; Chul Soon Yong. Enhanced solubility and oral bioavailability of itraconazole by combining membrane emulsification and spray drying technique. International Journal of Pharmaceutics. 2012, 434 (1-2), 264-271.

Span is a registered trademark of ICI Group.

Nonionic surfactant.

Other References

Merck
14,8724
Harmonized Tariff Code
3402.13
TSCA
Yes
RTECS
WG2920000

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