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551-06-4 - 1-Naphthyl isothiocyanate, 98% - L12418 - Alfa Aesar

L12418 1-Naphthyl isothiocyanate, 98%

CAS Number
551-06-4
Synonyms

Size Price ($) Quantity Availability
10g 98.20
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1-Naphthyl isothiocyanate, 98%

MDL
MFCD00003882
EINECS
208-990-8

Chemical Properties

Formula
C11H7NS
Formula Weight
185.25
Melting point
54-57°
Sensitivity
Moisture Sensitive
Solubility
Hydrolyzes in water.

Applications

1-Naphthyl isothiocyanate is a tool for the study of liver damage which causes bile stasis and hyperbilirubinemia acutely and bile duct hyperplasia and biliary cirrhosis chronically, with changes in hepatocyte function.

Notes

Moisture Sensitive. Incompatible with bases, alcohols and amines. Store under dry inert gas. Protect from humidity and water. Store away from moisture.

Literature References

Matthew Quinn; Yoshiyuki Ueno; Hae Yong Pae; Li Huang; Gabriel Frampton; Cheryl Galindo; Heather Francis; Darijana Horvat; Matthew McMillin; Sharon Demorrow. American Journal of Physiology - Gastrointestinal and Liver Physiology.2012, 302, (1), G182-G193.

Cen Guo; Lei He; Dan Yao; Jiye A; Bei Cao; Jin Ren; Guangji Wang; Guoyu Pan. Alpha-naphthylisothiocyanate modulates hepatobiliary transporters in sandwich-cultured rat hepatocytes. Toxicology Letters.2014, 224, (1), 93-100.

GHS Hazard and Precautionary Statements

Hazard Statements: H301-H311-H331-H314-H318

Toxic if swallowed. Toxic in contact with skin. Toxic if inhaled. Causes severe skin burns and eye damage. Causes serious eye damage.

Precautionary Statements: P260u-P301+P310a-P303+P361+P353-P305+P351+P338-P405-P501a

IF SWALLOWED: IF ON SKIN (or hair): Remove/Take off immediately all contaminated clothing. Rinse skin with water/shower. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. Store locked up. Dispose of contents/container in accordance with local/regional/national/international regulations.

Other References

Merck
14,6411
Beilstein
637868
Hazard Class
8
Packing Group
III
Harmonized Tariff Code
2930.90
TSCA
Yes
RTECS
NX9100000

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