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Trifluoroacetamidine is used as probe for determination of membrane potential and extra/intracellular volume of erythrocytes by fluorine-19 NMR studies. It is a reagent used as protected ammonia equivalent.
R E London; S A Gabel. Determination of membrane potential and cell volume by 19F NMR using trifluoroacetate and trifluoroacetamide probes. Biochemistry (Washington).1989, 28, (6), 2378-2382.
P Midoux; P Wahl; J C Auchet; M Monsigny. Fluorescence quenching of tryptophan by trifluoroacetamide. Biochimica et Biophysica Acta.1984, 801, (1), 16-25.
Hazard Statements: H314-H318
Causes severe skin burns and eye damage. Causes serious eye damage.
Precautionary Statements: P260u-P303+P361+P353-P305+P351+P338-P301+P330+P331-P405-P501a
IF ON SKIN (or hair): Remove/Take off immediately all contaminated clothing. Rinse skin with water/shower. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. IF SWALLOWED: Rinse mouth. Do NOT induce vomiting. Store locked up. Dispose of contents/container in accordance with local/regional/national/international regulations.