Sodium ethoxide, 21% w/w in ethanol is used as a strong base in organic synthesis. It finds application in various chemical reactions such as condensation, esterification, alkoxylation and etherifcation. It is actively involved in Claisen condensation, Stobbe reaction and Wolf-kishner reduction. It is an important starting material for the synthesis of ethyl ester and diethyl ester of malonic acid. In Williamson ether synthesis, it reacts with ethyl bromide to form diethyl ether.
Abduh, M. Y.; van Ulden, W.; Kalpoe, V.; van de Bovenkamp, H. H.; Manurung, R.; Heeres, H. J. Biodiesel synthesis from Jatropha curcas L. oil and ethanol in a continuous centrifugal contactor separator. Eur. J. Lipid Sci. Technol. 2013, 115 (1), 123-131.
Parsons, R. V.; Cenkowski, S.; Sorensen, J. L.; Beta, T.; Arntfield, S. D. Hemicellulose polysaccharide recovery from flax shive using alkaline solutions with sodium ethoxide pretreatment. Ind. Crops Prod. 2013, 44, 165-170.
Hazard Statements: H225-H314-H318
Highly flammable liquid and vapour. Causes severe skin burns and eye damage. Causes serious eye damage.
Precautionary Statements: P210-P260u-P303+P361+P353-P305+P351+P338-P405-P501a
Keep away from heat/sparks/open flames/hot surfaces. - No smoking. IF ON SKIN (or hair): Remove/Take off immediately all contaminated clothing. Rinse skin with water/shower. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. Store locked up. Dispose of contents/container in accordance with local/regional/national/international regulations.