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100-07-2 - 4-Methoxybenzoyl chloride, 97% - p-Anisoyl chloride - L13120 - Alfa Aesar

L13120 4-Methoxybenzoyl chloride, 97%

CAS Number
100-07-2
Synonyms
p-Anisoyl chloride

Size Price ($) Quantity Availability
25g 35.10
100g 88.68
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4-Methoxybenzoyl chloride, 97%

MDL
MFCD00000687
EINECS
202-816-4

Chemical Properties

Formula
C8H7ClO2
Formula Weight
170.60
Melting point
22°
Boiling Point
145°/14mm
Flash Point
87°(188°F)
Density
1.260
Refractive Index
1.5810
Sensitivity
Moisture Sensitive
Solubility
It reacts in water.

Applications

4-Methoxybenzoyl chloride is used in the synthesis of stilbene and dihydrostilbene derivatives as potential anti-cancer agents. It is also used in the synthesis of coumarin dimers with potential HIV-1 activity.

Notes

Moisture sensitive. Incompatible with oxidizing agents and bases.

Literature References

Martyn J.Earle; Paul B.McCormac; Kenneth R.Seddon. The first high yield green route to a pharmaceutical in a room temperature ionic liquid. Green Chem. 2000, 2,(6), 261-262.

 

Stephen T.Heller; Swaminathan R.Natarajan. 1,3-Diketones from acid chlorides and ketones:? A rapid and general one-pot synthesis of pyrazoles. Org. Lett. 2006, 8,(13), 2675-2678.

GHS Hazard and Precautionary Statements

Hazard Statements: H314-H318-H227

Causes severe skin burns and eye damage. Causes serious eye damage. Combustible liquid.

Precautionary Statements: P210-P260-P280-P303+P361+P353-P305+P351+P338-P301+P330+P331-P304+P340-P310-P405-P501a

Keep away from heat/sparks/open flames/hot surfaces. - No smoking. Do not breathe dust/fume/gas/mist/vapours/spray. Wear protective gloves/protective clothing/eye protection/face protection. IF ON SKIN (or hair): Remove/Take off immediately all contaminated clothing. Rinse skin with water/shower. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. IF SWALLOWED: Rinse mouth. Do NOT induce vomiting. IF INHALED: Remove to fresh air and keep at rest in a position comfortable for breathing. Immediately call a POISON CENTER or doctor/physician. Store locked up. Dispose of contents/container in accordance with local/regional/national/international regulations.

Other References

Merck
14,673
Beilstein
471918
Hazard Class
8
Packing Group
II
Harmonized Tariff Code
2918.99
TSCA
Yes

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