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L13159 Acridine Orange

CAS Number
10127-02-3
Synonyms
3,6-Bis(dimethylamino)acridine hydrochloride zinc chloride double salt
C.I. 46005

Stock No. Size Price ($) Quantity Availability
L13159-06 5g 22.30
L13159-14 25g 53.20
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Acridine Orange

MDL
MFCD00081043
EINECS
233-353-6

Chemical Properties

Formula
C17H19N3•HCl.ZnCl2
Formula Weight
438.10
Storage & Sensitivity
Hygroscopic. Store under Nitrogen. Ambient temperatures.
Solubility
Soluble in water.

Applications

Fluorescent stain for nucleic acids. An RNA polymerase inhibitorAcridine Orange acts as a lysosomal dye. It is used for cell-cycle studies. It plays an important role as a nucleic acid-selective fluorescent cationic dye, which is useful for cell cycle determination. Further, it serves as an inhibitor of RNA polymerase.

Notes

Hygroscopic. Incompatible with strong oxidizing agents.

Literature References

Biological stain.

Selvaggi, R.; Tarpani, L.; Santuari, A.; Giovagnoli, S.; Latterini, L. Silica nanoparticles assisted photodegradation of acridine orange in aqueous suspensions. Appl. Catal., B 2015, 168-169, 363-369.

Zhang, Y.; Pan, J.; Zhang, G.; Zhou, X. Intercalation of herbicide propyzamide into DNA using acridine orange as a fluorescence probe. Sens. Actuators, B 2015, 206, 630-639.

GHS Hazard and Precautionary Statements

Hazard Statements: H302-H312-H332-H341

Harmful if swallowed. Harmful in contact with skin. Harmful if inhaled. Suspected of causing genetic defects.

Precautionary Statements: P201-P202-P261-P264b-P270-P271-P281-P301+P312-P302+P352-P304+P340-P308+P313-P312-P330-P363-P501c

Obtain special instructions before use. Do not handle until all safety precautions have been read and understood. Avoid breathing dust/fume/gas/mist/vapours/spray. Wash face, hands and any exposed skin thoroughly after handling Do not eat, drink or smoke when using this product. Use only outdoors or in a well-ventilated area. Use personal protective equipment as required. IF SWALLOWED: Call a POISON CENTER or doctor/physician if you feel unwell. IF ON SKIN: Wash with plenty of soap and water. IF INHALED: Remove to fresh air and keep at rest in a position comfortable for breathing. IF exposed or concerned: Get medical advice/attention. Rinse mouth. Wash contaminated clothing before reuse. Dispose of contents/ container to an approved waste disposal plant

Other References

Beilstein
3734978
Harmonized Tariff Code
3204.19
TSCA
No
RTECS
AR7600000

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