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10127-02-3 - Acridine Orange - 3,6-Bis(dimethylamino)acridine hydrochloride zinc chloride double salt - C.I. 46005 - L13159 - Alfa Aesar

L13159 Acridine Orange

CAS Number
10127-02-3
Synonyms
3,6-Bis(dimethylamino)acridine hydrochloride zinc chloride double salt
C.I. 46005

Size Price ($) Quantity Availability
5g 21.22
25g 49.75
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Acridine Orange

MDL
MFCD00081043
EINECS
233-353-6

Chemical Properties

Formula
C17H19N3•HCl.ZnCl2
Formula Weight
438.10
Sensitivity
Hygroscopic
Solubility
Soluble in water.

Applications

Fluorescent stain for nucleic acids. An RNA polymerase inhibitorAcridine Orange acts as a lysosomal dye. It is used for cell-cycle studies. It plays an important role as a nucleic acid-selective fluorescent cationic dye, which is useful for cell cycle determination. Further, it serves as an inhibitor of RNA polymerase.

Notes

Hygroscopic. Incompatible with strong oxidizing agents.

Literature References

Biological stain.

Selvaggi, R.; Tarpani, L.; Santuari, A.; Giovagnoli, S.; Latterini, L. Silica nanoparticles assisted photodegradation of acridine orange in aqueous suspensions. Appl. Catal., B 2015, 168-169, 363-369.

Zhang, Y.; Pan, J.; Zhang, G.; Zhou, X. Intercalation of herbicide propyzamide into DNA using acridine orange as a fluorescence probe. Sens. Actuators, B 2015, 206, 630-639.

GHS Hazard and Precautionary Statements

Hazard Statements: H341

Suspected of causing genetic defects.

Precautionary Statements: P201-P281-P202-P308+P313-P405-P501a

Obtain special instructions before use. Use personal protective equipment as required. Do not handle until all safety precautions have been read and understood. IF exposed or concerned: Get medical advice/attention. Store locked up. Dispose of contents/container in accordance with local/regional/national/international regulations.

Other References

Beilstein
3734978
Harmonized Tariff Code
3204.19
TSCA
No
RTECS
AR7600000

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