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Fluorescent stain for nucleic acids. An RNA polymerase inhibitorAcridine Orange acts as a lysosomal dye. It is used for cell-cycle studies. It plays an important role as a nucleic acid-selective fluorescent cationic dye, which is useful for cell cycle determination. Further, it serves as an inhibitor of RNA polymerase.
Selvaggi, R.; Tarpani, L.; Santuari, A.; Giovagnoli, S.; Latterini, L. Silica nanoparticles assisted photodegradation of acridine orange in aqueous suspensions. Appl. Catal., B 2015, 168-169, 363-369.
Zhang, Y.; Pan, J.; Zhang, G.; Zhou, X. Intercalation of herbicide propyzamide into DNA using acridine orange as a fluorescence probe. Sens. Actuators, B 2015, 206, 630-639.
Hazard Statements: H341
Suspected of causing genetic defects.
Precautionary Statements: P260-P201-P280-P304+P340-P405-P501a
Do not breathe dust/fume/gas/mist/vapours/spray. Obtain special instructions before use. Wear protective gloves/protective clothing/eye protection/face protection. IF INHALED: Remove to fresh air and keep at rest in a position comfortable for breathing. Store locked up. Dispose of contents/container in accordance with local/regional/national/international regulations.